Sortase Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody Drug Conjugates with High In Vitro and In Vivo Potency.

by Roger R Beerli, Tamara Hell, Anna S Merkel, Ulf Grawunder
Published 2015-01-01

Novel Antibody Drug Conjugates Targeting Tumor-Associated Receptor Tyrosine Kinase ROR2 by Functional Screening of Fully Human Antibody Libraries Using Transpo-mAb Display on Proge...

by Ina Hellmann, Lorenz Waldmeier, Marie-Christine Bannwarth-Escher, Kseniya Maslova, Fabian I. Wolter, Ulf Grawunder, Roger R. Beerli
Published 2018-11-01

Generation of an artificial human B cell line test system using Transpo-mAbTM technology to evaluate the therapeutic efficacy of novel antigen-specific fusion proteins.

by Diana Klose, Mira Woitok, Judith Niesen, Roger R Beerli, Ulf Grawunder, Rainer Fischer, Stefan Barth, Rolf Fendel, Thomas Nachreiner
Published 2017-01-01

Cystatin F is a biomarker of prion pathogenesis in mice.

by Mario Nuvolone, Nicolas Schmid, Gino Miele, Silvia Sorce, Rita Moos, Christian Schori, Roger R Beerli, Monika Bauer, Philippe Saudan, Klaus Dietmeier, Ingolf Lachmann, Michael Linnebank, Roland Martin, Ulf Kallweit, Veronika Kana, Elisabeth J Rushing, Herbert Budka, Adriano Aguzzi
Published 2017-01-01

A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer

by Lucia D’Amico, Ulrike Menzel, Michael Prummer, Philipp Müller, Mélanie Buchi, Abhishek Kashyap, Ulrike Haessler, Alexander Yermanos, Rémy Gébleux, Manfred Briendl, Tamara Hell, Fabian I. Wolter, Roger R. Beerli, Iva Truxova, Špíšek Radek, Tatjana Vlajnic, Ulf Grawunder, Sai Reddy, Alfred Zippelius
Published 2019-01-01