Hook proteins: association with Alzheimer pathology and regulatory role of hook3 in amyloid beta generation.

by Lydia Herrmann, Caspar Wiegmann, Annika Arsalan-Werner, Isabel Hilbrich, Carsten Jäger, Katharina Flach, Anne Suttkus, Ingolf Lachmann, Thomas Arendt, Max Holzer
Published 2015-01-01

Development and Technical Validation of an Immunoassay for the Detection of APP_669–711 (Aβ_−3–40) in Biological Samples

by Hans W. Klafki, Petra Rieper, Anja Matzen, Silvia Zampar, Oliver Wirths, Jonathan Vogelgsang, Dirk Osterloh, Lara Rohdenburg, Timo J. Oberstein, Olaf Jahn, Isaak Beyer, Ingolf Lachmann, Hans-Joachim Knölker, Jens Wiltfang
Published 2020-09-01

Evaluation of cerebrospinal fluid proteins as potential biomarkers for early stage Parkinson's disease diagnosis.

by Marcia Cristina T Dos Santos, Dieter Scheller, Claudia Schulte, Irene R Mesa, Peter Colman, Sarah R Bujac, Rosie Bell, Caroline Berteau, Luis Tosar Perez, Ingolf Lachmann, Daniela Berg, Walter Maetzler, Andre Nogueira da Costa
Published 2018-01-01

Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread

by Gabor G. Kovacs, Leonid Breydo, Ryan Green, Viktor Kis, Gina Puska, Péter Lőrincz, Laura Perju-Dumbrava, Regina Giera, Walter Pirker, Mirjam Lutz, Ingolf Lachmann, Herbert Budka, Vladimir N. Uversky, Kinga Molnár, Lajos László
Published 2014-09-01

Differential diagnostic value of total alpha-synuclein assay in the cerebrospinal fluid between Alzheimer’s disease and dementia with Lewy bodies from the prodromal stage

by Olivier Bousiges, Nathalie Philippi, Thomas Lavaux, Armand Perret-Liaudet, Ingolf Lachmann, Caroline Schaeffer-Agalède, Pierre Anthony, Anne Botzung, Lucie Rauch, Barbara Jung, Paulo Loureiro de Sousa, Catherine Demuynck, Catherine Martin-Hunyadi, Benjamin Cretin, Frédéric Blanc
Published 2020-09-01

Cystatin F is a biomarker of prion pathogenesis in mice.

by Mario Nuvolone, Nicolas Schmid, Gino Miele, Silvia Sorce, Rita Moos, Christian Schori, Roger R Beerli, Monika Bauer, Philippe Saudan, Klaus Dietmeier, Ingolf Lachmann, Michael Linnebank, Roland Martin, Ulf Kallweit, Veronika Kana, Elisabeth J Rushing, Herbert Budka, Adriano Aguzzi
Published 2017-01-01

Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease

by Sonia M. Vallabh, Eric Vallabh Minikel, Victoria J. Williams, Becky C. Carlyle, Alison J. McManus, Chase D. Wennick, Anna Bolling, Bianca A. Trombetta, David Urick, Chloe K. Nobuhara, Jessica Gerber, Holly Duddy, Ingolf Lachmann, Christiane Stehmann, Steven J. Collins, Kaj Blennow, Henrik Zetterberg, Steven E. Arnold
Published 2020-06-01