Using a non-image-based medium-throughput assay for screening compounds targeting N-myristoylation in intracellular Leishmania amastigotes.

by Daniel Paape, Andrew S Bell, William P Heal, Jennie A Hutton, Robin J Leatherbarrow, Edward W Tate, Deborah F Smith
Published 2014-12-01

Diverse modes of binding in structures of Leishmania majorN-myristoyltransferase with selective inhibitors

by James A. Brannigan, Shirley M. Roberts, Andrew S. Bell, Jennie A. Hutton, Michael R. Hodgkinson, Edward W. Tate, Robin J. Leatherbarrow, Deborah F. Smith, Anthony J. Wilkinson
Published 2014-07-01

Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs.

by Andrew S Bell, James E Mills, Gareth P Williams, James A Brannigan, Anthony J Wilkinson, Tanya Parkinson, Robin J Leatherbarrow, Edward W Tate, Anthony A Holder, Deborah F Smith
Published 2012-01-01