Diverse modes of binding in structures of Leishmania majorN-myristoyltransferase with selective inhibitors

by James A. Brannigan, Shirley M. Roberts, Andrew S. Bell, Jennie A. Hutton, Michael R. Hodgkinson, Edward W. Tate, Robin J. Leatherbarrow, Deborah F. Smith, Anthony J. Wilkinson
Published 2014-07-01

The orthologue of Sjögren's syndrome nuclear autoantigen 1 (SSNA1) in Trypanosoma brucei is an immunogenic self-assembling molecule.

by Helen P Price, Michael R Hodgkinson, Rachel S Curwen, Lorna M MacLean, James A Brannigan, Mark Carrington, Barbara A Smith, David A Ashford, Meg Stark, Deborah F Smith
Published 2012-01-01

Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs.

by Andrew S Bell, James E Mills, Gareth P Williams, James A Brannigan, Anthony J Wilkinson, Tanya Parkinson, Robin J Leatherbarrow, Edward W Tate, Anthony A Holder, Deborah F Smith
Published 2012-01-01