Coming to terms with complexity: Limits to a reductionist view of aging

by Robert J Shmookler Reis
Published 2012-08-01

Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance.

by Cagdaş Tazearslan, Srinivas Ayyadevara, Puneet Bharill, Robert J Shmookler Reis
Published 2009-04-01

A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer’s Disease

by Samuel Kakraba, Srinivas Ayyadevara, Srinivas Ayyadevara, Narsimha Reddy Penthala, Meenakshisundaram Balasubramaniam, Akshatha Ganne, Ling Liu, Ramani Alla, Ramani Alla, Shoban Babu Bommagani, Steven W. Barger, Steven W. Barger, W. Sue T. Griffin, W. Sue T. Griffin, Peter A. Crooks, Robert J. Shmookler Reis, Robert J. Shmookler Reis, Robert J. Shmookler Reis
Published 2019-12-01

Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington’s disease

by Dmitry A. Nedosekin, TsungYen Chen, Srinivas Ayyadevara, Vladimir P. Zharov, Robert J. Shmookler Reis
Published 2021-10-01

Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aβ Self-Aggregation and Metal Chelation-Induced Aβ Aggregation

by Suresh K. Bowroju, Nirjal Mainali, Srinivas Ayyadevara, Narsimha R. Penthala, Sesha Krishnamachari, Samuel Kakraba, Robert J. Shmookler Reis, Peter A. Crooks
Published 2020-08-01

Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases

by Meenakshisundaram Balasubramaniam, Srinivas Ayyadevara, Akshatha Ganne, Samuel Kakraba, Narsimha Reddy Penthala, Xiuxia Du, Peter A. Crooks, Sue T. Griffin, Robert J. Shmookler Reis
Published 2019-10-01