Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases

by Meenakshisundaram Balasubramaniam, Srinivas Ayyadevara, Akshatha Ganne, Samuel Kakraba, Narsimha Reddy Penthala, Xiuxia Du, Peter A. Crooks, Sue T. Griffin, Robert J. Shmookler Reis
Published 2019-10-01

A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer’s Disease

by Samuel Kakraba, Srinivas Ayyadevara, Srinivas Ayyadevara, Narsimha Reddy Penthala, Meenakshisundaram Balasubramaniam, Akshatha Ganne, Ling Liu, Ramani Alla, Ramani Alla, Shoban Babu Bommagani, Steven W. Barger, Steven W. Barger, W. Sue T. Griffin, W. Sue T. Griffin, Peter A. Crooks, Robert J. Shmookler Reis, Robert J. Shmookler Reis, Robert J. Shmookler Reis
Published 2019-12-01