An Improved High Yield Total Synthesis and Cytotoxicity Study of the Marine Alkaloid Neoamphimedine: An ATP-Competitive Inhibitor of Topoisomerase IIα and Potent Anticancer Agent

by Linfeng Li, Adedoyin D. Abraham, Qiong Zhou, Hadi Ali, Jeremy V. O'Brien, Brayden D. Hamill, John J. Arcaroli, Wells A. Messersmith, Daniel V. LaBarbera
Published 2014-09-01

Neoamphimedine Circumvents Metnase-Enhanced DNA Topoisomerase IIα Activity Through ATP-Competitive Inhibition

by Philip Reigan, Brian G. Reid, Qiong Zhou, Amanda K. Ashley, Jac A. Nickoloff, Robert Hromas, Daniel V. LaBarbera, Courtney L. Amerin, Qun Li, Adedoyin D. Abraham, Byong Hoon Yoo, Jessica Ponder
Published 2011-11-01