Design, synthesis and activity of thio-linked arabinofuranosyl disaccharides against mycobacterial tuberculosis (MTB) and Mycobacterium avium complex (MAC)

by Naveen K. Khare, Franco J. Duarte, Robert C. Reynolds, Joseph A. Maddry
Published 2012-12-01

Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis.

by Veeraraghavan Usha, Judith V Hobrath, Sudagar S Gurcha, Robert C Reynolds, Gurdyal S Besra
Published 2012-01-01

Enhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian models.

by Sean Ekins, Robert C Reynolds, Scott G Franzblau, Baojie Wan, Joel S Freundlich, Barry A Bunin
Published 2013-01-01

Screening and Development of New Inhibitors of FtsZ from M. Tuberculosis.

by Bini Mathew, Judith Varady Hobrath, Larry Ross, Michele C Connelly, Hava Lofton, Malini Rajagopalan, R Kiplin Guy, Robert C Reynolds
Published 2016-01-01

Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria.

by Anuradha Alahari, Xavier Trivelli, Yann Guérardel, Lynn G Dover, Gurdyal S Besra, James C Sacchettini, Robert C Reynolds, Geoffrey D Coxon, Laurent Kremer
Published 2007-12-01

NSAIDs: Old Drugs Reveal New Anticancer Targets

by Gary A. Piazza, Adam B. Keeton, Heather N. Tinsley, Jason D. Whitt, Bernard D. Gary, Bini Mathew, Raj Singh, William E. Grizzle, Robert C. Reynolds
Published 2010-05-01

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target.

by Sudagar S Gurcha, Veeraraghavan Usha, Jonathan A G Cox, Klaus Fütterer, Katherine A Abrahams, Apoorva Bhatt, Luke J Alderwick, Robert C Reynolds, Nicholas J Loman, VijayaShankar Nataraj, Carlos Alemparte, David Barros, Adrian J Lloyd, Lluis Ballell, Judith V Hobrath, Gurdyal S Besra
Published 2014-01-01