Cloning-free CRISPR

by Mandana Arbab, Sharanya Srinivasan, Tatsunori Hashimoto, Niels Geijsen, Richard I. Sherwood
Published 2015-11-01

Cas9 Functionally Opens Chromatin.

by Amira A Barkal, Sharanya Srinivasan, Tatsunori Hashimoto, David K Gifford, Richard I Sherwood
Published 2016-01-01

Machine learning based CRISPR gRNA design for therapeutic exon skipping.

by Wilson Louie, Max W Shen, Zakir Tahiry, Sophia Zhang, Daniel Worstell, Christopher A Cassa, Richard I Sherwood, David K Gifford
Published 2021-01-01

An integrated model of multiple-condition ChIP-Seq data reveals predeterminants of Cdx2 binding.

by Shaun Mahony, Matthew D Edwards, Esteban O Mazzoni, Richard I Sherwood, Akshay Kakumanu, Carolyn A Morrison, Hynek Wichterle, David K Gifford
Published 2014-03-01

Small molecule inhibition of ATM kinase increases CRISPR-Cas9 1-bp insertion frequency

by Heysol C. Bermudez-Cabrera, Sannie Culbertson, Sammy Barkal, Benjamin Holmes, Max W. Shen, Sophia Zhang, David K. Gifford, Richard I. Sherwood
Published 2021-08-01

Detection of gene cis-regulatory element perturbations in single-cell transcriptomes.

by Grace Hui Ting Yeo, Oscar Juez, Qing Chen, Budhaditya Banerjee, Lendy Chu, Max W Shen, May Sabry, Ive Logister, Richard I Sherwood, David K Gifford
Published 2021-03-01

A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer

by Paola A. Betancur, Brian J. Abraham, Ying Y. Yiu, Stephen B. Willingham, Farnaz Khameneh, Mark Zarnegar, Angera H. Kuo, Kelly McKenna, Yoko Kojima, Nicholas J. Leeper, Po Ho, Phung Gip, Tomek Swigut, Richard I. Sherwood, Michael F. Clarke, George Somlo, Richard A. Young, Irving L. Weissman
Published 2017-04-01