Npas4: a neuronal transcription factor with a key role in social and cognitive functions relevant to developmental disorders.

by Laurence Coutellier, Simret Beraki, Pooneh Memar Ardestani, Nay Lui Saw, Mehrdad Shamloo
Published 2012-01-01

Critical values for plasma glucose in aggravating ischaemic brain damage: correlation to extracellular pH

by Ping-An Li, Mehrdad Shamloo, Ken-ichiro Katsura, Maj-Lis Smith, Bo K. Siesjö
Published 1995-04-01

Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis

by Amit U Joshi, Nay L Saw, Hannes Vogel, Anna D Cunnigham, Mehrdad Shamloo, Daria Mochly‐Rosen
Published 2018-03-01

Beta-adrenergic receptor antagonism is proinflammatory and exacerbates neuroinflammation in a mouse model of Alzheimer's Disease

by Andrew K. Evans, Pooneh M. Ardestani, Bitna Yi, Heui Hye Park, Rachel K. Lam, Mehrdad Shamloo
Published 2020-12-01

Intracerebral Delivery of Brain-Derived Neurotrophic Factor Using HyStem^®-C Hydrogel Implants Improves Functional Recovery and Reduces Neuroinflammation in a Rat Model o...

by Kristine Ravina, Denise I. Briggs, Sezen Kislal, Zuha Warraich, Tiffany Nguyen, Rachel K. Lam, Thomas I. Zarembinski, Mehrdad Shamloo
Published 2018-11-01

A pharmacological screening approach for discovery of neuroprotective compounds in ischemic stroke.

by Simret Beraki, Lily Litrus, Liza Soriano, Marie Monbureau, Lillian K To, Steven P Braithwaite, Karoly Nikolich, Roman Urfer, Donna Oksenberg, Mehrdad Shamloo
Published 2013-01-01

Enantiomers of 2-methylglutamate and 2-methylglutamine selectively impact mouse brain metabolism and behavior

by Adam M. Wawro, Chandresh R. Gajera, Steven A. Baker, Robert K. Leśniak, Curt R. Fischer, Nay L. Saw, Mehrdad Shamloo, Thomas J. Montine
Published 2021-04-01

Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down Syndrome: Activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer

by Mehrdad Faizi, Patrick L. Bader, Christine Tun, Angelo Encarnacion, Alexander Kleschevnikov, Pavel Belichenko, Nay Saw, Matthew Priestley, Richard W. Tsien, William C. Mobley, Mehrdad Shamloo
Published 2011-08-01

Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders.

by Bitna Yi, Alam Jahangir, Andrew K Evans, Denise Briggs, Kristine Ravina, Jacqueline Ernest, Amir B Farimani, Wenchao Sun, Jayakumar Rajadas, Michael Green, Evan N Feinberg, Vijay S Pande, Mehrdad Shamloo
Published 2017-01-01

Behavioral Abnormalities and Circuit Defects in the Basal Ganglia of a Mouse Model of 16p11.2 Deletion Syndrome

by Thomas Portmann, Mu Yang, Rong Mao, Georgia Panagiotakos, Jacob Ellegood, Gul Dolen, Patrick L. Bader, Brad A. Grueter, Carleton Goold, Elaine Fisher, Katherine Clifford, Pavitra Rengarajan, David Kalikhman, Darren Loureiro, Nay L. Saw, Zhou Zhengqui, Michael A. Miller, Jason P. Lerch, R. Mark Henkelman, Mehrdad Shamloo, Robert C. Malenka, Jacqueline N. Crawley, Ricardo E. Dolmetsch
Published 2014-05-01

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive de...

by Nicholas J Izzo, Agnes Staniszewski, Lillian To, Mauro Fa, Andrew F Teich, Faisal Saeed, Harrison Wostein, Thomas Walko, Anisha Vaswani, Meghan Wardius, Zanobia Syed, Jessica Ravenscroft, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Patricia Finn, Gary Look, Gilbert Rishton, Hank Safferstein, Miles Miller, Conrad Johanson, Edward Stopa, Manfred Windisch, Birgit Hutter-Paier, Mehrdad Shamloo, Ottavio Arancio, Harry LeVine, Susan M Catalano
Published 2014-01-01