Ethyl Pyruvate Emerges as a Safe and Fast Acting Agent against Trypanosoma brucei by Targeting Pyruvate Kinase Activity.

by Netsanet Worku, August Stich, Arwid Daugschies, Iris Wenzel, Randy Kurz, Rene Thieme, Susanne Kurz, Gerd Birkenmeier
Published 2015-01-01

Maternal Diabetes Leads to Adaptation in Embryonic Amino Acid Metabolism during Early Pregnancy.

by Jacqueline Gürke, Frank Hirche, René Thieme, Elisa Haucke, Maria Schindler, Gabriele I Stangl, Bernd Fischer, Anne Navarrete Santos
Published 2015-01-01

Ethyl Pyruvate Combats Human Leukemia Cells but Spares Normal Blood Cells.

by Gerd Birkenmeier, Nasr Y A Hemdan, Susanne Kurz, Marina Bigl, Philipp Pieroh, Tewodros Debebe, Martin Buchold, Rene Thieme, Gunnar Wichmann, Faramarz Dehghani
Published 2016-01-01

Analysis of Alpha-2 Macroglobulin from the Long-Lived and Cancer-Resistant Naked Mole-Rat and Human Plasma.

by René Thieme, Susanne Kurz, Marlen Kolb, Tewodros Debebe, Susanne Holtze, Michaela Morhart, Klaus Huse, Karol Szafranski, Matthias Platzer, Thomas B Hildebrandt, Gerd Birkenmeier
Published 2015-01-01

Nrf2/Keap1-Pathway Activation and Reduced Susceptibility to Chemotherapy Treatment by Acidification in Esophageal Adenocarcinoma Cells

by Lucie Storz, Philipp Walther, Olga Chemnitzer, Orestis Lyros, Stefan Niebisch, Matthias Mehdorn, Boris Jansen-Winkeln, Yusef Moulla, Thomas Büch, Ines Gockel, René Thieme
Published 2021-06-01

In-depth characterization of the Wnt-signaling/β-catenin pathway in an in vitro model of Barrett’s sequence

by Katharina Götzel, Olga Chemnitzer, Luisa Maurer, Arne Dietrich, Uwe Eichfeld, Orestis Lyros, Yusef Moulla, Stefan Niebisch, Matthias Mehdorn, Boris Jansen-Winkeln, Michael Vieth, Albrecht Hoffmeister, Ines Gockel, René Thieme
Published 2019-03-01

Linking Cancer Stem Cell Plasticity to Therapeutic Resistance-Mechanism and Novel Therapeutic Strategies in Esophageal Cancer

by Chenghui Zhou, Ningbo Fan, Fanyu Liu, Nan Fang, Patrick S. Plum, René Thieme, Ines Gockel, Sascha Gromnitza, Axel M. Hillmer, Seung-Hun Chon, Hans A. Schlösser, Christiane J. Bruns, Yue Zhao
Published 2020-06-01

The anti-tumorigenic activity of A2M-A lesson from the naked mole-rat.

by Susanne Kurz, René Thieme, Ronny Amberg, Marco Groth, Heinz-Georg Jahnke, Philipp Pieroh, Lars-Christian Horn, Marlen Kolb, Klaus Huse, Matthias Platzer, Daniela Volke, Faramarz Dehghani, Anton Buzdin, Kathrin Engel, Andrea Robitzki, Ralf Hoffmann, Ines Gockel, Gerd Birkenmeier
Published 2017-01-01

Correction: The anti-tumorigenic activity of A2M-A lesson from the naked mole-rat.

by Susanne Kurz, René Thieme, Ronny Amberg, Marco Groth, Heinz-Georg Jahnke, Philipp Pieroh, Lars-Christian Horn, Marlen Kolb, Klaus Huse, Matthias Platzer, Daniela Volke, Faramarz Dehghani, Anton Buzdin, Kathrin Engel, Andrea Robitzki, Ralf Hoffmann, Ines Gockel, Gerd Birkenmeier
Published 2018-01-01

CRBP-TS - evaluation of a home-based training and health care program for colorectal, breast, and prostate cancer using telemonitoring and self-management: study protocol for a ran...

by Roberto Falz, René Thieme, Uwe Tegtbur, Christian Bischoff, Christian Leps, Peter Hillemanns, Kay Kohlhaw, Jürgen Klempnauer, Florian Lordick, Jens-Uwe Stolzenburg, Bahriye Aktas, Jürgen Weitz, Ulrich Bork, Pauline Wimberger, Christian Thomas, Ronald Biemann, Boris Jansen-Winkeln, Antina Schulze, Ines Gockel, Martin Busse
Published 2021-02-01

Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases

by Jiyuan An, Puya Gharahkhani, Matthew H. Law, Jue-Sheng Ong, Xikun Han, Catherine M. Olsen, Rachel E. Neale, John Lai, Tom L. Vaughan, Ines Gockel, René Thieme, Anne C. Böhmer, Janusz Jankowski, Rebecca C. Fitzgerald, Johannes Schumacher, Claire Palles, BEACON, 23andMe Research Team, David C. Whiteman, Stuart MacGregor
Published 2019-09-01

Author Correction: Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases

by Jiyuan An, Puya Gharahkhani, Matthew H. Law, Jue-Sheng Ong, Xikun Han, Catherine M. Olsen, Rachel E. Neale, John Lai, Tom L. Vaughan, Ines Gockel, René Thieme, Anne C. Böhmer, Janusz Jankowski, Rebecca C. Fitzgerald, Johannes Schumacher, Claire Palles, BEACON, 23andMe Research Team, David C. Whiteman, Stuart MacGregor
Published 2019-12-01

Identification of loci of functional relevance to Barrett's esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative trait loci data from disease-relev...

by Julia Schröder, Vitalia Schüller, Andrea May, Christian Gerges, Mario Anders, Jessica Becker, Timo Hess, Nicole Kreuser, René Thieme, Kerstin U Ludwig, Tania Noder, Marino Venerito, Lothar Veits, Thomas Schmidt, Claudia Fuchs, Jakob R Izbicki, Arnulf H Hölscher, Dani Dakkak, Boris Jansen-Winkeln, Yusef Moulla, Orestis Lyros, Stefan Niebisch, Matthias Mehdorn, Hauke Lang, Dietmar Lorenz, Brigitte Schumacher, Rupert Mayershofer, Yogesh Vashist, Katja Ott, Michael Vieth, Josef Weismüller, Elisabeth Mangold, Markus M Nöthen, Susanne Moebus, Michael Knapp, Horst Neuhaus, Thomas Rösch, Christian Ell, Ines Gockel, Johannes Schumacher, Anne C Böhmer
Published 2019-01-01