Integrative approaches generate insights into the architecture of non-syndromic cleft lip with or without cleft palate

by Julia Welzenbach, Nigel L. Hammond, Miloš Nikolić, Frederic Thieme, Nina Ishorst, Elizabeth J. Leslie, Seth M. Weinberg, Terri H. Beaty, Mary L. Marazita, Elisabeth Mangold, Michael Knapp, Justin Cotney, Alvaro Rada-Iglesias, Michael J. Dixon, Kerstin U. Ludwig
Published 2021-07-01

TBK1 and TNFRSF13B mutations and an autoinflammatory disease in a child with lethal COVID-19

by Axel Schmidt, Sophia Peters, Alexej Knaus, Hemmen Sabir, Frauke Hamsen, Carlo Maj, Julia Fazaal, Sugirthan Sivalingam, Oleksandr Savchenko, Aakash Mantri, Dirk Holzinger, Ulrich Neudorf, Andreas Müller, Kerstin U. Ludwig, Peter M. Krawitz, Hartmut Engels, Markus M. Nöthen, Soyhan Bagci
Published 2021-07-01

Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data

by Eva Dunkhase, Kerstin U. Ludwig, Michael Knapp, Christine F. Skibola, Jane C. Figueiredo, Fay Julie Hosking, Eva Ellinghaus, Maria Teresa Landi, Hongxia Ma, Hidewaki Nakagawa, Jong-Won Kim, Jiali Han, Ping Yang, Anne C. Böhmer, Manuel Mattheisen, Markus M. Nöthen, Elisabeth Mangold
Published 2016-12-01

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology.

by Laurence J Howe, Myoung Keun Lee, Gemma C Sharp, George Davey Smith, Beate St Pourcain, John R Shaffer, Kerstin U Ludwig, Elisabeth Mangold, Mary L Marazita, Eleanor Feingold, Alexei Zhurov, Evie Stergiakouli, Jonathan Sandy, Stephen Richmond, Seth M Weinberg, Gibran Hemani, Sarah J Lewis
Published 2018-08-01

Meta-analysis Reveals Genome-Wide Significance at 15q13 for Nonsyndromic Clefting of Both the Lip and the Palate, and Functional Analyses Implicate GREM1 As a Plausible Causative G...

by Kerstin U Ludwig, Syeda Tasnim Ahmed, Anne C Böhmer, Nasim Bahram Sangani, Sheryil Varghese, Johanna Klamt, Hannah Schuenke, Pinar Gültepe, Andrea Hofmann, Michele Rubini, Khalid Ahmed Aldhorae, Regine P Steegers-Theunissen, Augusto Rojas-Martinez, Rudolf Reiter, Guntram Borck, Michael Knapp, Mitsushiro Nakatomi, Daniel Graf, Elisabeth Mangold, Heiko Peters
Published 2016-03-01

Genome-wide association study and meta-analysis identify ISL1 as genome-wide significant susceptibility gene for bladder exstrophy.

by Markus Draaken, Michael Knapp, Tracie Pennimpede, Johanna M Schmidt, Anne-Karolin Ebert, Wolfgang Rösch, Raimund Stein, Boris Utsch, Karin Hirsch, Thomas M Boemers, Elisabeth Mangold, Stefanie Heilmann, Kerstin U Ludwig, Ekkehart Jenetzky, Nadine Zwink, Susanne Moebus, Bernhard G Herrmann, Manuel Mattheisen, Markus M Nöthen, Michael Ludwig, Heiko Reutter
Published 2015-03-01

Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity

by Yanqin Yu, Xianbo Zuo, Miao He, Jinping Gao, Yuchuan Fu, Chuanqi Qin, Liuyan Meng, Wenjun Wang, Yaling Song, Yong Cheng, Fusheng Zhou, Gang Chen, Xiaodong Zheng, Xinhuan Wang, Bo Liang, Zhengwei Zhu, Xiazhou Fu, Yujun Sheng, Jiebing Hao, Zhongyin Liu, Hansong Yan, Elisabeth Mangold, Ingo Ruczinski, Jianjun Liu, Mary L. Marazita, Kerstin U. Ludwig, Terri H. Beaty, Xuejun Zhang, Liangdan Sun, Zhuan Bian
Published 2017-02-01

Exome sequencing in large, multiplex bipolar disorder families from Cuba.

by Anna Maaser, Andreas J Forstner, Jana Strohmaier, Julian Hecker, Kerstin U Ludwig, Sugirthan Sivalingam, Fabian Streit, Franziska Degenhardt, Stephanie H Witt, Céline S Reinbold, Anna C Koller, Ruth Raff, Stefanie Heilmann-Heimbach, Sascha B Fischer, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Stefan Herms, Per Hoffmann, Holger Thiele, Peter Nürnberg, Heide Löhlein Fier, Guillermo Orozco-Díaz, Deinys Carmenate-Naranjo, Niurka Proenza-Barzaga, Georg W J Auburger, Till F M Andlauer, Sven Cichon, Beatriz Marcheco-Teruel, Ole Mors, Marcella Rietschel, Markus M Nöthen
Published 2018-01-01

Identification of loci of functional relevance to Barrett's esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative trait loci data from disease-relev...

by Julia Schröder, Vitalia Schüller, Andrea May, Christian Gerges, Mario Anders, Jessica Becker, Timo Hess, Nicole Kreuser, René Thieme, Kerstin U Ludwig, Tania Noder, Marino Venerito, Lothar Veits, Thomas Schmidt, Claudia Fuchs, Jakob R Izbicki, Arnulf H Hölscher, Dani Dakkak, Boris Jansen-Winkeln, Yusef Moulla, Orestis Lyros, Stefan Niebisch, Matthias Mehdorn, Hauke Lang, Dietmar Lorenz, Brigitte Schumacher, Rupert Mayershofer, Yogesh Vashist, Katja Ott, Michael Vieth, Josef Weismüller, Elisabeth Mangold, Markus M Nöthen, Susanne Moebus, Michael Knapp, Horst Neuhaus, Thomas Rösch, Christian Ell, Ines Gockel, Johannes Schumacher, Anne C Böhmer
Published 2019-01-01