Autoimmune responses in the rheumatoid synovium.

by Rene E M Toes, Tom W J Huizinga
Published 2009-01-01

A Comparison of Immunoglobulin Variable Region N-Linked Glycosylation in Healthy Donors, Autoimmune Disease and Lymphoma

by Esther M. Vletter, Esther M. Vletter, Marvyn T. Koning, Hans Ulrich Scherer, Hendrik Veelken, Rene E. M. Toes
Published 2020-02-01

Anti-carbamylated protein antibodies precede disease onset in monkeys with collagen-induced arthritis

by Marije K. Verheul, Michel P. M. Vierboom, Bert A. ’t Hart, Rene E. M. Toes, Leendert A. Trouw
Published 2017-11-01

Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis

by Hester Koppejan, Diahann T. S. L. Jansen, Marjolijn Hameetman, Ranjeny Thomas, Rene E. M. Toes, Floris A. van Gaalen
Published 2019-01-01

Antibodies specific for carbamylated proteins precede the onset of clinical symptoms in mice with collagen induced arthritis.

by Jeroen N Stoop, Bi-Sheng Liu, Jing Shi, Diahann T S L Jansen, Martin Hegen, Tom W J Huizinga, Leendert A Trouw, René E M Toes
Published 2014-01-01

Interaction analysis between HLA-DRB1 shared epitope alleles and MHC class II transactivator CIITA gene with regard to risk of rheumatoid arthritis.

by Marcus Ronninger, Maria Seddighzadeh, Morten Christoph Eike, Darren Plant, Nina A Daha, Beate Skinningsrud, Jane Worthington, Tore K Kvien, Rene E M Toes, Benedicte A Lie, Lars Alfredsson, Leonid Padyukov
Published 2012-01-01

N-Glycosylation Site Analysis of Citrullinated Antigen-Specific B-Cell Receptors Indicates Alternative Selection Pathways During Autoreactive B-Cell Development

by Rochelle D. Vergroesen, Linda M. Slot, Barbera D. C. van Schaik, Marvyn T. Koning, Theo Rispens, Antoine H. C. van Kampen, Antoine H. C. van Kampen, René E. M. Toes, Hans U. Scherer
Published 2019-09-01

Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis.

by Linda M Slot, Rochelle D Vergroesen, Priscilla F Kerkman, Ellen Staudinger, Sanne Reijm, Hugo J van Dooren, Ellen I H van der Voort, Tom W J Huizinga, René E M Toes, Hans U Scherer
Published 2021-01-01

Circulating calprotectin (S100A8/A9) is higher in rheumatoid arthritis patients that relapse within 12 months of tapering anti-rheumatic drugs

by Emma C. de Moel, Jürgen Rech, Michael Mahler, Johannes Roth, Thomas Vogl, Anne Schouffoer, Robbert J. Goekoop, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Georg Schett, Diane van der Woude
Published 2019-12-01

In rheumatoid arthritis, changes in autoantibody levels reflect intensity of immunosuppression, not subsequent treatment response

by Emma C. de Moel, Veerle F. A. M. Derksen, Leendert A. Trouw, Holger Bang, Gerard Collée, Leroy R. Lard, Sofia Ramiro, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Diane van der Woude
Published 2019-01-01

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes

by Emma C. de Moel, Veerle F. A. M. Derksen, Gerrie Stoeken, Leendert A. Trouw, Holger Bang, Robbert J. Goekoop, Irene Speyer, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Diane van der Woude
Published 2018-02-01

The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical

by Debbie M. Boeters, Lukas Mangnus, Sofia Ajeganova, Elisabet Lindqvist, Björn Svensson, René E. M. Toes, Leendert A. Trouw, Tom W. J. Huizinga, Francis Berenbaum, Jacques Morel, Solbritt Rantapää-Dahlqvist, Annette H. M. van der Helm-van Mil
Published 2017-05-01

The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

by Myrthe A. M. van Delft, Marije K. Verheul, Leonie E. Burgers, Veerle F. A. M. Derksen, Annette H. M. van der Helm-van Mil, Diane van der Woude, Tom W. J. Huizinga, René E. M. Toes, Leendert A. Trouw
Published 2017-08-01

Circulating immunoglobulins are not associated with intraplaque mast cell number and other vulnerable plaque characteristics in patients with carotid artery stenosis.

by Sanne Willems, Daniël van der Velden, Paul H A Quax, Gert Jan de Borst, Jean-Paul P M de Vries, Frans L Moll, Johan Kuiper, René E M Toes, Saskia C A de Jager, Dominique P V de Kleijn, Imo E Hoefer, Gerard Pasterkamp, Ilze Bot
Published 2014-01-01

A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis.

by Fina A S Kurreeman, Leonid Padyukov, Rute B Marques, Steven J Schrodi, Maria Seddighzadeh, Gerrie Stoeken-Rijsbergen, Annette H M van der Helm-van Mil, Cornelia F Allaart, Willem Verduyn, Jeanine Houwing-Duistermaat, Lars Alfredsson, Ann B Begovich, Lars Klareskog, Tom W J Huizinga, Rene E M Toes
Published 2007-09-01

Correction: A Candidate Gene Approach Identifies the Region as a Risk Factor for Rheumatoid Arthritis.

by Fina A. S Kurreeman, Leonid Padyukov, Rute B Marques, Steven J Schrodi, Maria Seddighzadeh, Gerrie Stoeken-Rijsbergen, Annette H. M van der Helm-van Mil, Cornelia F Allaart, Willem Verduyn, Jeanine Houwing-Duistermaat, Lars Alfredsson, Ann B Begovich, Lars Klareskog, Tom W. J Huizinga, Rene E. M Toes
Published 2007-12-01

A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2.

by Monica Chang, Charles M Rowland, Veronica E Garcia, Steven J Schrodi, Joseph J Catanese, Annette H M van der Helm-van Mil, Kristin G Ardlie, Christopher I Amos, Lindsey A Criswell, Daniel L Kastner, Peter K Gregersen, Fina A S Kurreeman, Rene E M Toes, Tom W J Huizinga, Michael F Seldin, Ann B Begovich
Published 2008-06-01

Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load

by Sanne Reijm, Theresa Kissel, Gerrie Stoeken-Rijsbergen, Linda M. Slot, Corrie M. Wortel, Hugo J. van Dooren, Nivine E. W. Levarht, Arieke S. B. Kampstra, Veerle F. A. M. Derksen, Pleuni Ooijevaar-de Heer, Holger Bang, Jan W. Drijfhout, Leendert A. Trouw, Tom W. J. Huizinga, Theo Rispens, Hans U. Scherer, René E. M. Toes
Published 2021-09-01

Lack of high BMI-related features in adipocytes and inflammatory cells in the infrapatellar fat pad (IFP)

by Anja J. de Jong, Inge R. Klein-Wieringa, Stefan N. Andersen, Joanneke C. Kwekkeboom, Linda Herb-van Toorn, Badelog J. E. de Lange-Brokaar, Danny van Delft, John Garcia, Wu Wei, Huub J. L. van der Heide, Yvonne M. Bastiaansen-Jenniskens, Gerjo J. V. M. van Osch, Annemarie M. Zuurmond, Vedrana Stojanovic-Susulic, Rob G. H. H. Nelissen, René E. M. Toes, Margreet Kloppenburg, Andreea Ioan-Facsinay
Published 2017-08-01

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.

by Jing Cui, Eli A Stahl, Saedis Saevarsdottir, Corinne Miceli, Dorothee Diogo, Gosia Trynka, Towfique Raj, Maša Umiċeviċ Mirkov, Helena Canhao, Helena Canhao, Katsunori Ikari, Chikashi Terao, Yukinori Okada, Sara Wedrén, Johan Askling, Hisashi Yamanaka, Shigeki Momohara, Atsuo Taniguchi, Koichiro Ohmura, Fumihiko Matsuda, Tsuneyo Mimori, Namrata Gupta, Manik Kuchroo, Ann W Morgan, John D Isaacs, Anthony G Wilson, Kimme L Hyrich, Marieke Herenius, Marieke E Doorenspleet, Paul-Peter Tak, J Bart A Crusius, Irene E van der Horst-Bruinsma, Gert Jan Wolbink, Piet L C M van Riel, Mart van de Laar, Henk-Jan Guchelaar, Nancy A Shadick, Cornelia F Allaart, Tom W J Huizinga, Rene E M Toes, Robert P Kimberly, S Louis Bridges, Lindsey A Criswell, Larry W Moreland, João Eurico Fonseca, Niek de Vries, Barbara E Stranger, Philip L De Jager, Soumya Raychaudhuri, Michael E Weinblatt, Peter K Gregersen, Xavier Mariette, Anne Barton, Leonid Padyukov, Marieke J H Coenen, Elizabeth W Karlson, Robert M Plenge
Published 2013-03-01