Small Molecule Cjoc42 Improves Chemo-Sensitivity and Increases Levels of Tumor Suppressor Proteins in Hepatoblastoma Cells and in Mice by Inhibiting Oncogene Gankyrin

by Amber M. D’Souza, Amber M. D’Souza, Ashley Cast, Meenasri Kumbaji, Maria Rivas, Ruhi Gulati, Michael Johnston, Michael Johnston, David Smithrud, James Geller, Nikolai Timchenko, Nikolai Timchenko
Published 2021-03-01

Liver Proliferation Is an Essential Driver of Fibrosis in Mouse Models of Nonalcoholic Fatty Liver Disease

by Ashley Cast, Meenasri Kumbaji, Amber D'Souza, Katherine Rodriguez, Anita Gupta, Rebekah Karns, Lubov Timchenko, Nikolai Timchenko
Published 2019-08-01

Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte ProliferationSummary

by Amber M. D’Souza, Yanjun Jiang, Ashley Cast, Leila Valanejad, Mary Wright, Kyle Lewis, Meenasri Kumbaji, Sheeniza Shah, David Smithrud, Rebekah Karns, Soona Shin, Nikolai Timchenko
Published 2018-01-01

Hepatoblastomas exhibit marked downregulation driven by promoter DNA hypermethylation

by Maria Prates Rivas, Talita Ferreira Marques Aguiar, Mariana Maschietto, Renan B Lemes, Luiz Carlos Caires-Júnior, Ernesto Goulart, Kayque Alves Telles-Silva, Estela Novak, Lilian Maria Cristofani, Vicente Odone, Monica Cypriano, Silvia Regina Caminada de Toledo, Dirce Maria Carraro, Melissa Quintero Escobar, Hana Lee, Michael Johnston, Cecilia Maria Lima da Costa, Isabela Werneck da Cunha, Ljubica Tasic, Peter L Pearson, Carla Rosenberg, Nikolai Timchenko, Ana Cristina Victorino Krepischi
Published 2020-12-01