ADP-ribosylation factor 6 mediates E-cadherin recovery by chemical chaperones.

by Joana Figueiredo, Joana Simões-Correia, Ola Söderberg, Gianpaolo Suriano, Raquel Seruca
Published 2011-01-01

E-cadherin destabilization accounts for the pathogenicity of missense mutations in hereditary diffuse gastric cancer.

by Joana Simões-Correia, Joana Figueiredo, Rui Lopes, François Stricher, Carla Oliveira, Luis Serrano, Raquel Seruca
Published 2012-01-01

The Extracellular Matrix: An Accomplice in Gastric Cancer Development and Progression

by Ana Margarida Moreira, Joana Pereira, Soraia Melo, Maria Sofia Fernandes, Patrícia Carneiro, Raquel Seruca, Joana Figueiredo
Published 2020-02-01

E-cadherin signal sequence disruption: a novel mechanism underlying hereditary cancer

by Joana Figueiredo, Soraia Melo, Kimberley Gamet, Tanis Godwin, Susana Seixas, João M. Sanches, Parry Guilford, Raquel Seruca
Published 2018-08-01

A machine learning approach for single cell interphase cell cycle staging

by Hemaxi Narotamo, Maria Sofia Fernandes, Ana Margarida Moreira, Soraia Melo, Raquel Seruca, Margarida Silveira, João Miguel Sanches
Published 2021-09-01

Predicting the Functional Impact of CDH1 Missense Mutations in Hereditary Diffuse Gastric Cancer

by Soraia Melo, Joana Figueiredo, Maria Sofia Fernandes, Margarida Gonçalves, Eurico Morais-de-Sá, João Miguel Sanches, Raquel Seruca
Published 2017-12-01

Loss and recovery of Mgat3 and GnT-III Mediated E-cadherin N-glycosylation is a mechanism involved in epithelial-mesenchymal-epithelial transitions.

by Salomé S Pinho, Patrícia Oliveira, Joana Cabral, Sandra Carvalho, David Huntsman, Fátima Gärtner, Raquel Seruca, Celso A Reis, Carla Oliveira
Published 2012-01-01

<i>Helicobacter Pylori</i> Targets the EPHA2 Receptor Tyrosine Kinase in Gastric Cells Modulating Key Cellular Functions

by Marina Leite, Miguel S. Marques, Joana Melo, Marta T. Pinto, Bruno Cavadas, Miguel Aroso, Maria Gomez-Lazaro, Raquel Seruca, Ceu Figueiredo
Published 2020-02-01

The bacterial protein azurin impairs invasion and FAK/Src signaling in P-cadherin-overexpressing breast cancer cell models.

by Nuno Bernardes, Ana Sofia Ribeiro, Sofia Abreu, Bruna Mota, Rute G Matos, Cecilia M Arraiano, Raquel Seruca, Joana Paredes, Arsenio M Fialho
Published 2013-01-01

CCAAT/enhancer binding protein β (C/EBPβ) isoforms as transcriptional regulators of the pro-invasive CDH3/P-cadherin gene in human breast cancer cells.

by André Albergaria, Carlos Resende, Ana Rita Nobre, Ana Sofia Ribeiro, Bárbara Sousa, José Carlos Machado, Raquel Seruca, Joana Paredes, Fernando Schmitt, Fernando Schmitt
Published 2013-01-01

CLMP is essential for intestinal development, but does not play a key role in cellular processes involved in intestinal epithelial development.

by Christine S van der Werf, Nai-Hua Hsiao, Siobhan Conroy, Joana Paredes, Ana S Ribeiro, Yunia Sribudiani, Raquel Seruca, Robert M W Hofstra, Helga Westers, Sven C D van Ijzendoorn
Published 2013-01-01

Insulin/IGF-I signaling pathways enhances tumor cell invasion through bisecting GlcNAc N-glycans modulation. an interplay with E-cadherin.

by Julio Cesar Madureira de-Freitas-Junior, Sandra Carvalho, Ana M Dias, Patrícia Oliveira, Joana Cabral, Raquel Seruca, Carla Oliveira, José Andrés Morgado-Díaz, Celso A Reis, Salomé S Pinho
Published 2013-01-01

Docosahexaenoic acid inhibits Helicobacter pylori growth in vitro and mice gastric mucosa colonization.

by Marta Correia, Valérie Michel, António A Matos, Patrícia Carvalho, Maria J Oliveira, Rui M Ferreira, Marie-Agnès Dillies, Michel Huerre, Raquel Seruca, Ceu Figueiredo, Jose C Machado, Eliette Touati
Published 2012-01-01

Intricate Macrophage-Colorectal Cancer Cell Communication in Response to Radiation.

by Ana T Pinto, Marta L Pinto, Sérgia Velho, Marta T Pinto, Ana P Cardoso, Rita Figueira, Armanda Monteiro, Margarida Marques, Raquel Seruca, Mário A Barbosa, Marc Mareel, Maria J Oliveira, Sónia Rocha
Published 2016-01-01

S100P is a molecular determinant of E-cadherin function in gastric cancer

by Patrícia Carneiro, Ana Margarida Moreira, Joana Figueiredo, Rita Barros, Patrícia Oliveira, Maria Sofia Fernandes, Anabela Ferro, Raquel Almeida, Carla Oliveira, Fátima Carneiro, Fernando Schmitt, Joana Paredes, Sérgia Velho, Raquel Seruca
Published 2019-11-01

Crosstalk between Helicobacter pylori and gastric epithelial cells is impaired by docosahexaenoic acid.

by Marta Correia, Valérie Michel, Hugo Osório, Meriem El Ghachi, Mathilde Bonis, Ivo G Boneca, Hilde De Reuse, António A Matos, Pascal Lenormand, Raquel Seruca, Ceu Figueiredo, Jose Carlos Machado, Eliette Touati
Published 2013-01-01

Germline <i>CDH1</i> G212E Missense Variant: Combining Clinical, In Vitro and In Vivo Strategies to Unravel Disease Burden

by Joana Figueiredo, Fátima Mercadillo, Soraia Melo, Alicia Barroso, Margarida Gonçalves, José Díaz-Tasende, Patrícia Carneiro, Luis Robles, Francisco Colina, Carolina Ibarrola, José Perea, Eurico Morais-de-Sá, Raquel Seruca, Miguel Urioste
Published 2021-08-01

SRC inhibition prevents P-cadherin mediated signaling and function in basal-like breast cancer cells

by Ana Sofia Ribeiro, Ana Rita Nobre, Nuno Mendes, João Almeida, André Filipe Vieira, Bárbara Sousa, Filomena A. Carvalho, Joana Monteiro, António Polónia, Martina Fonseca, João Miguel Sanches, Nuno C. Santos, Raquel Seruca, Joana Paredes
Published 2018-11-01

Hereditary Gastric and Breast Cancer Syndromes Related to CDH1 Germline Mutation: A Multidisciplinary Clinical Review

by Giovanni Corso, Giacomo Montagna, Joana Figueiredo, Carlo La Vecchia, Uberto Fumagalli Romario, Maria Sofia Fernandes, Susana Seixas, Franco Roviello, Cristina Trovato, Elena Guerini-Rocco, Nicola Fusco, Gabriella Pravettoni, Serena Petrocchi, Anna Rotili, Giulia Massari, Francesca Magnoni, Francesca De Lorenzi, Manuela Bottoni, Viviana Galimberti, João Miguel Sanches, Mariarosaria Calvello, Raquel Seruca, Bernardo Bonanni
Published 2020-06-01

The Porto European Cancer Research Summit 2021

by Ulrik Ringborg, Anton Berns, Julio E. Celis, Manuel Heitor, Josep Tabernero, Joachim Schüz, Michael Baumann, Rui Henrique, Matti Aapro, Partha Basu, Regina Beets‐Tan, Benjamin Besse, Fátima Cardoso, Fátima Carneiro, Guy vanden Eede, Alexander Eggermont, Stefan Fröhling, Susan Galbraith, Elena Garralda, Douglas Hanahan, Thomas Hofmarcher, Bengt Jönsson, Olli Kallioniemi, Miklós Kásler, Eva Kondorosi, Jan Korbel, Denis Lacombe, José Carlos Machado, José M. Martin‐Moreno, Francoise Meunier, Péter Nagy, Paolo Nuciforo, Simon Oberst, Júlio Oliveiera, Maria Papatriantafyllou, Walter Ricciardi, Alexander Roediger, Bettina Ryll, Richard Schilsky, Grazia Scocca, Raquel Seruca, Marta Soares, Karen Steindorf, Vincenzo Valentini, Emile Voest, Elisabete Weiderpass, Nils Wilking, Amanda Wren, Laurence Zitvogel
Published 2021-10-01