Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments

by Zhang, Feng, Pinello, Luca
Published 2020

Multi-scale chromatin state annotation using a hierarchical hidden Markov model

by Huang, Jialiang, Glass, Kimberly, Pinello, Luca, Yuan, Guo-Cheng, Marco Rubio, Eugenio, Meuleman, Wouter, Wang, Jianrong, Kellis, Manolis
Published 2017

CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data

by Hsu, Jonathan Y., Fulco, Charles P., Farouni, Rick, Clement, Kendell, Engreitz, Jesse Michael, Lander, Eric Steven, Pinello, Luca
Published 2020

BRCA1 Recruitment to Transcriptional Pause Sites Is Required for R-Loop-Driven DNA Damage Repair

by Hatchi, Elodie, Skourti-Stathaki, Konstantina, Ventz, Steffen, Pinello, Luca, Yen, Angela, Kamieniarz-Gdula, Kinga, Dimitrov, Stoil, Pathania, Shailja, McKinney, Kristine M, Kellis, Manolis, Hill, Sarah J, Parmigiani, Giovanni, Proudfoot, Nicholas J, Livingston, David M, Eaton, Matthew Lucas
Published 2016

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

by Canver, Matthew C., Smith, Elenoe C., Sher, Falak, Pinello, Luca, Shalem, Ophir, Chen, Diane D., Schupp, Patrick G., Vinjamur, Divya S., Garcia, Sara P., Luc, Sidinh, Kurita, Ryo, Nakamura, Yukio, Fujiwara, Yuko, Maeda, Takahiro, Yuan, Guo-Cheng, Zhang, Feng, Orkin, Stuart H., Bauer, Daniel E., Sanjana, Neville
Published 2016

The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells

by Beyaz, Semir, Kim, Ji Hyung, Pinello, Luca, Huang, Jialiang, Kerenyi, Marc A, Das, Partha P, Barnitz, R Anthony, Herault, Aurelie, Haining, W Nicholas, Passegue, Emmanuelle, Yuan, Guo-Cheng, Orkin, Stuart H, Winau, Florian, Xifaras, Michael, Dogum, Rizkullah, Yilmaz, Omer, Hu, Yu,M.C.P.Massachusetts Institute of Technology
Published 2018

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

by Saadatpour, Assieh, Hong, Sue-Jean, Pinello, Luca, Katz, Yarden, Lamming, Dudley W., Guo, Guoji, Bell, George W., Selig, Martin, Nielsen, G. Petur, Gupta, Nitin, Ferrone, Cristina R., Deshpande, Vikram, Yuan, Guo-Cheng, Orkin, Stuart H., Beyaz, Semir, Mana, Miyeko, Roper, Jatin, Kedrin, Dmitriy, Bauer-Rowe, Khristian E., Xifaras, Michael, Akkad, Adam, Arias, Erika, Shinagare, Shweta, Abu-Remaileh, Monther, Dogum, Rizkullah, Sabatini, David, Yilmaz, Omer, Mihaylova, Maria M.
Published 2017