Nuclear Localization of the Autism Candidate Gene Neurobeachin and Functional Interaction with the NOTCH1 Intracellular Domain Indicate a Role in Regulating Transcription.

by Krizia Tuand, Pieter Stijnen, Karolien Volders, Jeroen Declercq, Kim Nuytens, Sandra Meulemans, John Creemers
Published 2016-01-01

The dwarf phenotype in GH240B mice, haploinsufficient for the autism candidate gene Neurobeachin, is caused by ectopic expression of recombinant human growth hormone.

by Kim Nuytens, Krizia Tuand, Quili Fu, Pieter Stijnen, Vincent Pruniau, Sandra Meulemans, Hugo Vankelecom, John W M Creemers
Published 2014-01-01

Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth

by Jeroen Declercq, Bas Brouwers, Vincent P. E. G. Pruniau, Pieter Stijnen, Krizia Tuand, Sandra Meulemans, Annik Prat, Nabil G. Seidah, Abdel-Majid Khatib, John W. M. Creemers
Published 2015-01-01

Metabolic and Behavioural Phenotypes in Nestin-Cre Mice Are Caused by Hypothalamic Expression of Human Growth Hormone.

by Jeroen Declercq, Bas Brouwers, Vincent P E G Pruniau, Pieter Stijnen, Geoffroy de Faudeur, Krizia Tuand, Sandra Meulemans, Lutgarde Serneels, Anica Schraenen, Frans Schuit, John W M Creemers
Published 2015-01-01

Haploinsufficiency of the autism candidate gene Neurobeachin induces autism-like behaviors and affects cellular and molecular processes of synaptic plasticity in mice

by Kim Nuytens, Ilse Gantois, Pieter Stijnen, Emilia Iscru, Annelies Laeremans, Lutgarde Serneels, Lien Van Eylen, Stephen A. Liebhaber, Koen Devriendt, Detlef Balschun, Lutgarde Arckens, John W.M. Creemers, Rudi D'Hooge
Published 2013-03-01