The Transcription Factor ATF4 Promotes Expression of Cell Stress Genes and Cardiomyocyte Death in a Cellular Model of Atrial Fibrillation

by Johanna K. Freundt, Gerrit Frommeyer, Fabian Wötzel, Andreas Huge, Andreas Hoffmeier, Sven Martens, Lars Eckardt, Philipp S. Lange
Published 2018-01-01

Network analyses reveal pervasive functional regulation between proteases in the human protease web.

by Nikolaus Fortelny, Jennifer H Cox, Reinhild Kappelhoff, Amanda E Starr, Philipp F Lange, Paul Pavlidis, Christopher M Overall
Published 2014-05-01

Antiarrhythmic Effect of Ranolazine in Combination with Selective NCX-Inhibition in an Experimental Model of Atrial Fibrillation

by Julian Wolfes, Christian Ellermann, Niklas Broer, Benjamin Rath, Kevin Willy, Patrick Robert Leitz, Philipp Sebastian Lange, Lars Eckardt, Gerrit Frommeyer
Published 2020-10-01

Proteomic amino-termini profiling reveals targeting information for protein import into complex plastids.

by Pitter F Huesgen, Meriem Alami, Philipp F Lange, Leonard J Foster, Wolfgang P Schröder, Christopher M Overall, Beverley R Green
Published 2013-01-01

Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure

by Johanna K. Freundt, Gerrit Frommeyer, Tilmann Spieker, Fabian Wötzel, Jochen Schulze Grotthoff, Jörg Stypmann, Georg Hempel, Michael Schäfers, Andreas H. Jacobs, Lars Eckardt, Philipp S. Lange
Published 2019-03-01

Quantifying Left Atrial Size in the Context of Atrial Fibrillation Ablation: Which Echocardiographic Method Correlates to Outcome of Pulmonary Venous Isolation?

by Patrick Leitz, Lena Marie Stebel, Christian Andresen, Christian Ellermann, Fatih Güner, Florian Reinke, Simon Kochhäuser, Gerrit Frommeyer, Julia Köbe, Kristina Wasmer, Philipp S. Lange, Stefan Orwat, Lars Eckardt, Dirk G. Dechering
Published 2021-09-01

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors

by Anna Prudova, Vasilena Gocheva, Ulrich auf dem Keller, Ulrich Eckhard, Oakley C. Olson, Leila Akkari, Georgina S. Butler, Nikolaus Fortelny, Philipp F. Lange, Jennifer C. Mark, Johanna A. Joyce, Christopher M. Overall
Published 2016-08-01

PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways

by Anuli C. Uzozie, Enes K. Ergin, Nina Rolf, Janice Tsui, Amanda Lorentzian, Samuel S. H. Weng, Lorenz Nierves, Theodore G. Smith, C. James Lim, Christopher A. Maxwell, Gregor S. D. Reid, Philipp F. Lange
Published 2021-03-01

Multi-Omic Approach to Identify Phenotypic Modifiers Underlying Cerebral Demyelination in X-Linked Adrenoleukodystrophy

by Phillip A. Richmond, Frans van der Kloet, Frans van der Kloet, Frederic M. Vaz, Frederic M. Vaz, David Lin, Anuli Uzozie, Anuli Uzozie, Emma Graham, Michael Kobor, Sara Mostafavi, Perry D. Moerland, Philipp F. Lange, Philipp F. Lange, Antoine H. C. van Kampen, Antoine H. C. van Kampen, Wyeth W. Wasserman, Marc Engelen, Marc Engelen, Stephan Kemp, Stephan Kemp, Stephan Kemp, Clara D. M. van Karnebeek, Clara D. M. van Karnebeek, Clara D. M. van Karnebeek
Published 2020-06-01

Macrophage Matrix Metalloproteinase-12 Dampens Inflammation and Neutrophil Influx in Arthritis

by Caroline L. Bellac, Antoine Dufour, Michael J. Krisinger, Anantasak Loonchanta, Amanda E. Starr, Ulrich auf dem Keller, Philipp F. Lange, Verena Goebeler, Reinhild Kappelhoff, Georgina S. Butler, Leslie D. Burtnick, Edward M. Conway, Clive R. Roberts, Christopher M. Overall
Published 2014-10-01

Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14

by Ulrich Eckhard, Pitter F. Huesgen, Oliver Schilling, Caroline L. Bellac, Georgina S. Butler, Jennifer H. Cox, Antoine Dufour, Verena Goebeler, Reinhild Kappelhoff, Ulrich auf dem Keller, Theo Klein, Philipp F. Lange, Giada Marino, Charlotte J. Morrison, Anna Prudova, David Rodriguez, Amanda E. Starr, Yili Wang, Christopher M. Overall
Published 2016-06-01

HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development

by Marisa Connell, Helen Chen, Jihong Jiang, Chia-Wei Kuan, Abbas Fotovati, Tony LH Chu, Zhengcheng He, Tess C Lengyell, Huaibiao Li, Torsten Kroll, Amanda M Li, Daniel Goldowitz, Lucien Frappart, Aspasia Ploubidou, Millan S Patel, Linda M Pilarski, Elizabeth M Simpson, Philipp F Lange, Douglas W Allan, Christopher A Maxwell
Published 2017-10-01