STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation

by Dongyao Yan, Hao-Wei Wang, Robert L. Bowman, Johanna A. Joyce
Published 2016-09-01

Iron imaging reveals tumor and metastasis macrophage hemosiderin deposits in breast cancer.

by Avigdor Leftin, Nir Ben-Chetrit, Florian Klemm, Johanna A Joyce, Jason A Koutcher
Published 2017-01-01

Identification and characterization of poorly differentiated invasive carcinomas in a mouse model of pancreatic neuroendocrine tumorigenesis.

by Karen E Hunter, Marsha L Quick, Anguraj Sadanandam, Douglas Hanahan, Johanna A Joyce
Published 2013-01-01

Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents

by Oakley C. Olson, Hyunjung Kim, Daniela F. Quail, Emily A. Foley, Johanna A. Joyce
Published 2017-04-01

Sensing cytosolic RpsL by macrophages induces lysosomal cell death and termination of bacterial infection.

by Wenhan Zhu, Lili Tao, Marsha L Quick, Johanna A Joyce, Jie-Ming Qu, Zhao-Qing Luo
Published 2015-03-01

Genetic and pharmacological targeting of CSF-1/CSF-1R inhibits tumor-associated macrophages and impairs BRAF-induced thyroid cancer progression.

by Mabel Ryder, Matti Gild, Tobias M Hohl, Eric Pamer, Jeff Knauf, Ronald Ghossein, Johanna A Joyce, James A Fagin
Published 2013-01-01

Deficiency for the cysteine protease cathepsin L impairs Myc-induced tumorigenesis in a mouse model of pancreatic neuroendocrine cancer.

by Nicola R Brindle, Johanna A Joyce, Fanya Rostker, Elizabeth R Lawlor, Lamorna Swigart-Brown, Gerard Evan, Douglas Hanahan, Ksenya Shchors
Published 2015-01-01

Correction: Live Imaging of Cysteine-Cathepsin Activity Reveals Dynamics of Focal Inflammation, Angiogenesis, and Polyp Growth

by Elias Gounaris, Ching H. Tung, Clifford Restaino, René Maehr, Rainer Kohler, Johanna A. Joyce, Hidde L. Ploegh, Terrence A. Barrett, Ralph Weissleder, Khashayarsha Khazaie
Published 2008-01-01

Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth.

by Elias Gounaris, Ching H Tung, Clifford Restaino, René Maehr, Rainer Kohler, Johanna A Joyce, Hidde L Ploegh, Terrence A Barrett, Ralph Weissleder, Khashayarsha Khazaie
Published 2008-08-01

Correction: Live Imaging of Cysteine-Cathepsin Activity Reveals Dynamics of Focal Inflammation, Angiogenesis, and Polyp Growth.

by Elias Gounaris, Ching H. Tung, Clifford Restaino, René Maehr, Rainer Kohler, Johanna A. Joyce, Hidde L. Ploegh, Terrence A. Barrett, Ralph Weissleder, Khashayarsha Khazaie
Published 2008-01-01

Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway.

by Peihong Dai, Weiyi Wang, Hua Cao, Francesca Avogadri, Lianpan Dai, Ingo Drexler, Johanna A Joyce, Xiao-Dong Li, Zhijian Chen, Taha Merghoub, Stewart Shuman, Liang Deng
Published 2014-04-01

Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation

by Saara Hämälistö, Jonathan Lucien Stahl, Elena Favaro, Qing Yang, Bin Liu, Line Christoffersen, Ben Loos, Claudia Guasch Boldú, Johanna A. Joyce, Thomas Reinheckel, Marin Barisic, Marja Jäättelä
Published 2020-01-01

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors

by Anna Prudova, Vasilena Gocheva, Ulrich auf dem Keller, Ulrich Eckhard, Oakley C. Olson, Leila Akkari, Georgina S. Butler, Nikolaus Fortelny, Philipp F. Lange, Jennifer C. Mark, Johanna A. Joyce, Christopher M. Overall
Published 2016-08-01

Evaluating Magnetic Resonance Spectroscopy as a Tool for Monitoring Therapeutic Response of Whole Brain Radiotherapy in a Mouse Model for Breast-to-Brain Metastasis

by Woon Hyung Chae, Katja Niesel, Michael Schulz, Michael Schulz, Florian Klemm, Johanna A. Joyce, Marcus Prümmer, Boris Brill, Judith Bergs, Judith Bergs, Franz Rödel, Franz Rödel, Franz Rödel, Ulrich Pilatus, Lisa Sevenich, Lisa Sevenich, Lisa Sevenich
Published 2019-11-01