P-loop residues critical for selectivity in K channels fail to confer selectivity to rabbit HCN4 channels.

by Nazzareno D'Avanzo, Roman Pekhletski, Peter H Backx
Published 2009-11-01

Changes in Heart Rate and Its Regulation by the Autonomic Nervous System Do Not Differ Between Forced and Voluntary Exercise in Mice

by Robert Lakin, Robert Lakin, Camilo Guzman, Farzad Izaddoustdar, Nazari Polidovitch, Nazari Polidovitch, Jack M. Goodman, Jack M. Goodman, Peter H. Backx, Peter H. Backx
Published 2018-07-01

A Porcine Model of Heart Failure With Preserved Ejection Fraction Induced by Chronic Pressure Overload Characterized by Cardiac Fibrosis and Remodeling

by Weijiang Tan, Xiang Li, Shuang Zheng, Xiaohui Li, Xiaoshen Zhang, W. Glen Pyle, Honghua Chen, Jian Wu, Huan Sun, Yunzeng Zou, Peter H. Backx, Peter H. Backx, Feng Hua Yang, Feng Hua Yang
Published 2021-06-01

Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.

by Jie Liu, Kyoung-Han Kim, Michael J Morales, Scott P Heximer, Chi-Chung Hui, Peter H Backx
Published 2015-01-01

Slit2 Protects Hearts Against Ischemia-Reperfusion Injury by Inhibiting Inflammatory Responses and Maintaining Myofilament Contractile Properties

by Xiang Li, Shuang Zheng, Shuang Zheng, Weijiang Tan, Hongqi Chen, Xiaohui Li, Jian Wu, Ting Luo, Xuecong Ren, W. Glen Pyle, Lijing Wang, Peter H. Backx, Peter H. Backx, Ren Huang, Feng Hua Yang, Feng Hua Yang
Published 2020-03-01

Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome

by Jiani C. Yin, Mathew J. Platt, Xixi Tian, Xue Wu, Peter H. Backx, Jeremy A. Simpson, Toshiyuki Araki, Benjamin G. Neel
Published 2017-05-01

Transcriptomic Bioinformatic Analyses of Atria Uncover Involvement of Pathways Related to Strain and Post-translational Modification of Collagen in Increased Atrial Fibrillation Vu...

by Yena Oh, Yena Oh, Yena Oh, Yena Oh, Sibao Yang, Sibao Yang, Xueyan Liu, Xueyan Liu, Sayantan Jana, Farzad Izaddoustdar, Xiaodong Gao, Ryan Debi, Dae-Kyum Kim, Dae-Kyum Kim, Kyoung-Han Kim, Kyoung-Han Kim, Ping Yang, Zamaneh Kassiri, Robert Lakin, Peter H. Backx, Peter H. Backx
Published 2020-12-01

Complex interactions in a novel SCN5A compound mutation associated with long QT and Brugada syndrome: Implications for Na+ channel blocking pharmacotherapy for de novo conduction d...

by Jie Liu, Jason D Bayer, Roozbeh Aschar-Sobbi, Marianne Wauchop, Danna Spears, Michael Gollob, Edward J Vigmond, Robert Tsushima, Peter H Backx, Vijay S Chauhan
Published 2018-01-01

Constitutive smooth muscle tumour necrosis factor regulates microvascular myogenic responsiveness and systemic blood pressure

by Jeffrey T. Kroetsch, Andrew S. Levy, Hangjun Zhang, Roozbeh Aschar-Sobbi, Darcy Lidington, Stefan Offermanns, Sergei A. Nedospasov, Peter H. Backx, Scott P. Heximer, Steffen-Sebastian Bolz
Published 2017-04-01

Modeling Atrial Fibrillation using Human Embryonic Stem Cell-Derived Atrial Tissue

by Zachary Laksman, Marianne Wauchop, Eric Lin, Stephanie Protze, Jeehoon Lee, Wallace Yang, Farzad Izaddoustdar, Sanam Shafaattalab, Lior Gepstein, Glen F. Tibbits, Gordon Keller, Peter H. Backx
Published 2017-07-01

Revisiting right anterior oblique projections for the triangle of Koch: implications from computed tomography

by Yanjing Wang, Lin Liu, Robert Lakin, Nazari Polidovitch, Guohui Liu, Hongliang Yang, Ming Yu, Mingzhou Yan, Dong Zhao, Peter H. Backx, Huan Sun, Yuquan He, Ping Yang
Published 2020-08-01

Apelin increases atrial conduction velocity, refractoriness, and prevents inducibility of atrial fibrillation

by Young M. Kim, Robert Lakin, Hao Zhang, Jack Liu, Ayaaz Sachedina, Maneesh Singh, Emily Wilson, Marco Perez, Subodh Verma, Thomas Quertermous, Jeffrey Olgin, Peter H. Backx, Euan A. Ashley
Published 2020-09-01

Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts.

by Linn S Strandberg, Xuezhi Cui, Arianna Rath, Jie Liu, Earl D Silverman, Xiaoru Liu, Vinayakumar Siragam, Cameron Ackerley, Brenda Bin Su, Jane Yuqing Yan, Marco Capecchi, Luca Biavati, Alice Accorroni, William Yuen, Filippo Quattrone, Kalvin Lung, Edgar T Jaeggi, Peter H Backx, Charles M Deber, Robert M Hamilton
Published 2013-01-01

CFTR Therapeutics Normalize Cerebral Perfusion Deficits in Mouse Models of Heart Failure and Subarachnoid Hemorrhage

by Darcy Lidington, PhD, Jessica C. Fares, MSc, Franziska E. Uhl, PhD, Danny D. Dinh, MSc, Jeffrey T. Kroetsch, PhD, Meghan Sauvé, PhD, Firhan A. Malik, PhD, Frank Matthes, PhD, Lotte Vanherle, MSc, Arman Adel, BSc, Abdul Momen, MD, PhD, Hangjun Zhang, MD, Roozbeh Aschar-Sobbi, PhD, Warren D. Foltz, PhD, Hoyee Wan, BSc, Manabu Sumiyoshi, MD, R. Loch Macdonald, MD, PhD, Mansoor Husain, MD, Peter H. Backx, PhD, DVM, Scott P. Heximer, PhD, Anja Meissner, PhD, Steffen-Sebastian Bolz, MD, PhD
Published 2019-12-01