Kif3a controls murine nephron number via GLI3 repressor, cell survival, and gene expression in a lineage-specific manner.

by Lijun Chi, Alevtina Galtseva, Lin Chen, Rong Mo, Chi-Chung Hui, Norman D Rosenblum
Published 2013-01-01

Antagonistic and cooperative actions of Kif7 and Sufu define graded intracellular Gli activities in Hedgehog signaling.

by Kelvin King Lo Law, Shigeru Makino, Rong Mo, Xiaoyun Zhang, Vijitha Puviindran, Chi-Chung Hui
Published 2012-01-01

Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.

by Jie Liu, Kyoung-Han Kim, Michael J Morales, Scott P Heximer, Chi-Chung Hui, Peter H Backx
Published 2015-01-01

Adult Gli2+/-;Gli3Δ699/+ Male and Female Mice Display a Spectrum of Genital Malformation.

by Fei He, Pedram Akbari, Rong Mo, Jennifer J Zhang, Chi-Chung Hui, Peter C Kim, Walid A Farhat
Published 2016-01-01

GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells.

by Jason E Cain, Epshita Islam, Fiona Haxho, Lin Chen, Darren Bridgewater, Erica Nieuwenhuis, Chi-Chung Hui, Norman D Rosenblum
Published 2009-10-01

A new Cre driver mouse line, Tcf21/Pod1-Cre, targets metanephric mesenchyme.

by Yoshiro Maezawa, Matthew Binnie, Chengjin Li, Paul Thorner, Chi-Chung Hui, Benjamin Alman, Makoto Mark Taketo, Susan E Quaggin
Published 2012-01-01

GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis

by Sabrina Coquenlorge, Wen-Chi Yin, Theodora Yung, Jingyi Pan, Xiaoyun Zhang, Rong Mo, Jaques Belik, Chi-chung Hui, Tae-Hee Kim
Published 2019-06-01

Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals

by Theodora Yung, Frankie Poon, Minggao Liang, Sabrina Coquenlorge, Emily C. McGaugh, Chi-chung Hui, Michael D. Wilson, M. Cristina Nostro, Tae-Hee Kim
Published 2019-10-01

T396I mutation of mouse Sufu reduces the stability and activity of Gli3 repressor.

by Shigeru Makino, Olena Zhulyn, Rong Mo, Vijitha Puviindran, Xiaoyun Zhang, Takuya Murata, Ryutaro Fukumura, Yuichi Ishitsuka, Hayato Kotaki, Daisuke Matsumaru, Shunsuke Ishii, Chi-Chung Hui, Yoichi Gondo
Published 2015-01-01

Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries.

by Anqi Fu, Sydney M Oberholtzer, Stefan Bagheri-Fam, Raphael H Rastetter, Claire Holdreith, Valeria L Caceres, Steven V John, Sarah A Shaw, Kathleen J Krentz, Xiaoyun Zhang, Chi-Chung Hui, Dagmar Wilhelm, Joan S Jorgensen
Published 2018-08-01

Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches

by Ji-Eun Kim, Lijiang Fei, Wen-Chi Yin, Sabrina Coquenlorge, Abilasha Rao-Bhatia, Xiaoyun Zhang, Sammy Shun Wai Shi, Ju Hee Lee, Noah A. Hahn, Wasi Rizvi, Kyoung-Han Kim, Hoon-Ki Sung, Chi-chung Hui, Guoji Guo, Tae-Hee Kim
Published 2020-01-01

Imbalance of Excitatory/Inhibitory Neuron Differentiation in Neurodevelopmental Disorders with an NR2F1 Point Mutation

by Ke Zhang, Fang Yu, Jian Zhu, Sue Han, Jiehui Chen, Xuanyuan Wu, Yingying Chen, Tingyu Shen, Jiaoyang Liao, Wenke Guo, Xianfa Yang, Ran Wang, Yun Qian, Jiaxin Yang, Leping Cheng, Yun Zhao, Chi-Chung Hui, Jinsong Li, Guangdun Peng, Shuijin He, Naihe Jing, Ke Tang
Published 2020-04-01

Distinct roles of UVRAG and EGFR signaling in skeletal muscle homeostasis

by Min Jeong Kim, Daniella Febbraro, Sofia Farkona, Taylor Gillmore, Joe Eun Son, Romario Regeenes, Huntley H. Chang, Evan Pollock-Tahiri, Jiaqi Yang, Yoo Jin Park, Tharini Sivasubramaniyam, Soo Jung Oh, Punit Saraon, Igor Stagljar, Jonathan V. Rocheleau, Chi-Chung Hui, Isabella Caniggia, Zhenyu Hao, Tak W. Mak, Ana Konvalinka, Minna Woo
Published 2021-05-01

The transcriptional landscape of Shh medulloblastoma

by Patryk Skowron, Hamza Farooq, Florence M. G. Cavalli, A. Sorana Morrissy, Michelle Ly, Liam D. Hendrikse, Evan Y. Wang, Haig Djambazian, Helen Zhu, Karen L. Mungall, Quang M. Trinh, Tina Zheng, Shizhong Dai, Ana S. Guerreiro Stucklin, Maria C. Vladoiu, Vernon Fong, Borja L. Holgado, Carolina Nor, Xiaochong Wu, Diala Abd-Rabbo, Pierre Bérubé, Yu Chang Wang, Betty Luu, Raul A. Suarez, Avesta Rastan, Aaron H. Gillmor, John J. Y. Lee, Xiao Yun Zhang, Craig Daniels, Peter Dirks, David Malkin, Eric Bouffet, Uri Tabori, James Loukides, François P. Doz, Franck Bourdeaut, Olivier O. Delattre, Julien Masliah-Planchon, Olivier Ayrault, Seung-Ki Kim, David Meyronet, Wieslawa A. Grajkowska, Carlos G. Carlotti, Carmen de Torres, Jaume Mora, Charles G. Eberhart, Erwin G. Van Meir, Toshihiro Kumabe, Pim J. French, Johan M. Kros, Nada Jabado, Boleslaw Lach, Ian F. Pollack, Ronald L. Hamilton, Amulya A. Nageswara Rao, Caterina Giannini, James M. Olson, László Bognár, Almos Klekner, Karel Zitterbart, Joanna J. Phillips, Reid C. Thompson, Michael K. Cooper, Joshua B. Rubin, Linda M. Liau, Miklós Garami, Peter Hauser, Kay Ka Wai Li, Ho-Keung Ng, Wai Sang Poon, G. Yancey Gillespie, Jennifer A. Chan, Shin Jung, Roger E. McLendon, Eric M. Thompson, David Zagzag, Rajeev Vibhakar, Young Shin Ra, Maria Luisa Garre, Ulrich Schüller, Tomoko Shofuda, Claudia C. Faria, Enrique López-Aguilar, Gelareh Zadeh, Chi-Chung Hui, Vijay Ramaswamy, Swneke D. Bailey, Steven J. Jones, Andrew J. Mungall, Richard A. Moore, John A. Calarco, Lincoln D. Stein, Gary D. Bader, Jüri Reimand, Jiannis Ragoussis, William A. Weiss, Marco A. Marra, Hiromichi Suzuki, Michael D. Taylor
Published 2021-03-01