NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between α-Adducin and Myosin X.

by Miguel A Brieño-Enríquez, Stefannie L Moak, J Kim Holloway, Paula E Cohen
Published 2017-01-01

MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis.

by J Kim Holloway, James Booth, Winfried Edelmann, Clare H McGowan, Paula E Cohen
Published 2008-09-01

NEK1 Facilitates Cohesin Removal during Mammalian Spermatogenesis

by Paula E. Cohen, Edward Nieves, Nadine K. Kolas, Kelly L. Corbett, Elle C. Roberson, Kim Holloway
Published 2011-03-01

Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing.

by Kathryn J Grive, Yang Hu, Eileen Shu, Andrew Grimson, Olivier Elemento, Jennifer K Grenier, Paula E Cohen
Published 2019-03-01

Mutation of the ATPase Domain of MutS Homolog-5 (MSH5) Reveals a Requirement for a Functional MutSγ Complex for All Crossovers in Mammalian Meiosis

by Carolyn R. Milano, J. Kim Holloway, Yongwei Zhang, Bo Jin, Cameron Smith, Aviv Bergman, Winfried Edelmann, Paula E. Cohen
Published 2019-06-01

Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis.

by J Kim Holloway, Swapna Mohan, Gabriel Balmus, Xianfei Sun, Andrew Modzelewski, Peter L Borst, Raimundo Freire, Robert S Weiss, Paula E Cohen
Published 2011-06-01

Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1γ-WAPL Axis in the Mouse

by Miguel A. Brieño-Enríquez, Stefannie L. Moak, Melissa Toledo, Joshua J. Filter, Stephen Gray, José L. Barbero, Paula E. Cohen, J. Kim Holloway
Published 2016-10-01

A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I.

by Melissa Toledo, Xianfei Sun, Miguel A Brieño-Enríquez, Vandana Raghavan, Stephen Gray, Jeffrey Pea, Carolyn R Milano, Anita Venkatesh, Lekha Patel, Peter L Borst, Eric Alani, Paula E Cohen
Published 2019-06-01

Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance...

by Amy M Lyndaker, Pei Xin Lim, Joanna M Mleczko, Catherine E Diggins, J Kim Holloway, Rebecca J Holmes, Rui Kan, Donald H Schlafer, Raimundo Freire, Paula E Cohen, Robert S Weiss
Published 2013-01-01

Genetic recombination is targeted towards gene promoter regions in dogs.

by Adam Auton, Ying Rui Li, Jeffrey Kidd, Kyle Oliveira, Julie Nadel, J Kim Holloway, Jessica J Hayward, Paula E Cohen, John M Greally, Jun Wang, Jun Wang, Carlos D Bustamante, Adam R Boyko
Published 2013-01-01

Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.

by Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby, Alejandro Lloret, Edith Lopez, Jason St Claire, Gagan B Panigrahi, Caixia Hou, Kim Holloway, Tammy Gillis, Jolene R Guide, Paula E Cohen, Guo-Min Li, Christopher E Pearson, Mark J Daly, Vanessa C Wheeler
Published 2013-10-01