HdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation.

by Jeffrey B Carroll, Amy Deik, Elisa Fossale, Rory M Weston, Jolene R Guide, Jamshid Arjomand, Seung Kwak, Clary B Clish, Marcy E MacDonald
Published 2015-01-01

Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.

by Marina Kovalenko, Ella Dragileva, Jason St Claire, Tammy Gillis, Jolene R Guide, Jaclyn New, Hualing Dong, Raju Kucherlapati, Melanie H Kucherlapati, Michelle E Ehrlich, Jong-Min Lee, Vanessa C Wheeler
Published 2012-01-01

Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.

by Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby, Alejandro Lloret, Edith Lopez, Jason St Claire, Gagan B Panigrahi, Caixia Hou, Kim Holloway, Tammy Gillis, Jolene R Guide, Paula E Cohen, Guo-Min Li, Christopher E Pearson, Mark J Daly, Vanessa C Wheeler
Published 2013-10-01