EMT and Stemness—Key Players in Pancreatic Cancer Stem Cells

by Eva Rodriguez-Aznar, Lisa Wiesmüller, Bruno Sainz, Patrick C. Hermann
Published 2019-08-01

The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures

by Sonia Alcalá, Paola Martinelli, Patrick C. Hermann, Christopher Heeschen, Bruno Sainz
Published 2019-01-01

The CXCL12 Crossroads in Cancer Stem Cells and Their Niche

by Juan Carlos López-Gil, Laura Martin-Hijano, Patrick C. Hermann, Bruno Sainz
Published 2021-01-01

The Cancer Stem Cell in Hepatocellular Carcinoma

by Lucas-Alexander Schulte, Juan Carlos López-Gil, Bruno Sainz, Patrick C. Hermann
Published 2020-03-01

The role of pluripotency factors to drive stemness in gastrointestinal cancer

by Martin Müller, Patrick C. Hermann, Stefan Liebau, Clair Weidgang, Thomas Seufferlein, Alexander Kleger, Lukas Perkhofer
Published 2016-03-01

Concentration of Bone Marrow Total Nucleated Cells by a Point-of-Care Device Provides a High Yield and Preserves Their Functional Activity

by Patrick C. Hermann, Stephan L. Huber, Tanja Herrler, Christoph Von Hesler, Joachim Andrassy, Sherwin V. Kevy, May S. Jacobson, Christopher Heeschen
Published 2007-11-01

Deletion of NEMO Inhibits EMT and Reduces Metastasis in KPC Mice

by Miltiadis Tsesmelis, Kanishka Tiwary, Katja Steiger, Nadine Sperb, Melanie Gerstenlauer, Uta Manfras, Harald J. Maier, Patrick C. Hermann, Lap Kwan Chan, Thomas Wirth
Published 2021-09-01

Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts.

by Patrick C Hermann, Sara M Trabulo, Bruno Sainz, Anamaria Balic, Elena Garcia, Stephan A Hahn, Mallaredy Vandana, Sanjeeb K Sahoo, Patrizia Tunici, Annette Bakker, Manuel Hidalgo, Christopher Heeschen
Published 2013-01-01

MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo

by Karolin Walter, Kanishka Tiwary, Marija Trajkovic-Arsic, Ana Hidalgo-Sastre, Laura Dierichs, Sven T. Liffers, Jiangning Gu, Johann Gout, Lucas-Alexander Schulte, Jan Münch, Thomas Seufferlein, Bruno Sainz, Jens T. Siveke, Eva Rodriguez-Aznar, Patrick C. Hermann
Published 2019-01-01

ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity

by Sonia Alcalá, Patricia Sancho, Paola Martinelli, Diego Navarro, Coral Pedrero, Laura Martín-Hijano, Sandra Valle, Julie Earl, Macarena Rodríguez-Serrano, Laura Ruiz-Cañas, Katerin Rojas, Alfredo Carrato, Laura García-Bermejo, Miguel Ángel Fernández-Moreno, Patrick C. Hermann, Bruno Sainz
Published 2020-05-01

Tbx3 fosters pancreatic cancer growth by increased angiogenesis and activin/nodal-dependent induction of stemness

by Lukas Perkhofer, Karolin Walter, Ivan G. Costa, Maria C. Romero Carrasco, Tim Eiseler, Susanne Hafner, Felicitas Genze, Martin Zenke, Wendy Bergmann, Anett Illing, Meike Hohwieler, Ralf Köhntop, Qiong Lin, Karl-Heinz Holzmann, Thomas Seufferlein, Martin Wagner, Stefan Liebau, Patrick C. Hermann, Alexander Kleger, Martin Müller
Published 2016-09-01

Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells

by Sandra Valle, Sonia Alcalá, Laura Martin-Hijano, Pablo Cabezas-Sáinz, Diego Navarro, Edurne Ramos Muñoz, Lourdes Yuste, Kanishka Tiwary, Karolin Walter, Laura Ruiz-Cañas, Marta Alonso-Nocelo, Juan A. Rubiolo, Emilio González-Arnay, Christopher Heeschen, Laura Garcia-Bermejo, Patrick C. Hermann, Laura Sánchez, Patricia Sancho, Miguel Ángel Fernández-Moreno, Bruno Sainz
Published 2020-10-01

Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells

by Karolin Walter, Eva Rodriguez-Aznar, Monica S. Ventura Ferreira, Pierre-Olivier Frappart, Tabea Dittrich, Kanishka Tiwary, Sabine Meessen, Laura Lerma, Nora Daiss, Lucas-Alexander Schulte, Zeynab Najafova, Frank Arnold, Valentyn Usachov, Ninel Azoitei, Mert Erkan, Andre Lechel, Tim H. Brümmendorf, Thomas Seufferlein, Alexander Kleger, Enrique Tabarés, Cagatay Günes, Steven A. Johnsen, Fabian Beier, Bruno Sainz, Patrick C. Hermann
Published 2021-06-01

Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration

by Frank Arnold, Pallavi U Mahaddalkar, Johann M. Kraus, Xiaowei Zhong, Wendy Bergmann, Dharini Srinivasan, Johann Gout, Elodie Roger, Alica K. Beutel, Eugen Zizer, Umesh Tharehalli, Nora Daiss, Ronan Russell, Lukas Perkhofer, Rupert Oellinger, Qiong Lin, Ninel Azoitei, Frank‐Ulrich Weiss, Markus M. Lerch, Stefan Liebau, Sarah‐Fee Katz, André Lechel, Roland Rad, Thomas Seufferlein, Hans A. Kestler, Michael Ott, Amar Deep Sharma, Patrick C. Hermann, Alexander Kleger
Published 2021-07-01