Deletion of NEMO Inhibits EMT and Reduces Metastasis in KPC Mice

by Miltiadis Tsesmelis, Kanishka Tiwary, Katja Steiger, Nadine Sperb, Melanie Gerstenlauer, Uta Manfras, Harald J. Maier, Patrick C. Hermann, Lap Kwan Chan, Thomas Wirth
Published 2021-09-01

MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo

by Karolin Walter, Kanishka Tiwary, Marija Trajkovic-Arsic, Ana Hidalgo-Sastre, Laura Dierichs, Sven T. Liffers, Jiangning Gu, Johann Gout, Lucas-Alexander Schulte, Jan Münch, Thomas Seufferlein, Bruno Sainz, Jens T. Siveke, Eva Rodriguez-Aznar, Patrick C. Hermann
Published 2019-01-01

Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells

by Sandra Valle, Sonia Alcalá, Laura Martin-Hijano, Pablo Cabezas-Sáinz, Diego Navarro, Edurne Ramos Muñoz, Lourdes Yuste, Kanishka Tiwary, Karolin Walter, Laura Ruiz-Cañas, Marta Alonso-Nocelo, Juan A. Rubiolo, Emilio González-Arnay, Christopher Heeschen, Laura Garcia-Bermejo, Patrick C. Hermann, Laura Sánchez, Patricia Sancho, Miguel Ángel Fernández-Moreno, Bruno Sainz
Published 2020-10-01

Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells

by Karolin Walter, Eva Rodriguez-Aznar, Monica S. Ventura Ferreira, Pierre-Olivier Frappart, Tabea Dittrich, Kanishka Tiwary, Sabine Meessen, Laura Lerma, Nora Daiss, Lucas-Alexander Schulte, Zeynab Najafova, Frank Arnold, Valentyn Usachov, Ninel Azoitei, Mert Erkan, Andre Lechel, Tim H. Brümmendorf, Thomas Seufferlein, Alexander Kleger, Enrique Tabarés, Cagatay Günes, Steven A. Johnsen, Fabian Beier, Bruno Sainz, Patrick C. Hermann
Published 2021-06-01