Assessing the Selectivity of FXR, LXRs, CAR, and RORγ Pharmaceutical Ligands With Reporter Cell Lines

by Lucia Toporova, Marina Grimaldi, Abdelhay Boulahtouf, Patrick Balaguer
Published 2020-07-01

In Vitro Cytochrome P450 Formation of a Mono-Hydroxylated Metabolite of Zearalenone Exhibiting Estrogenic Activities: Possible Occurrence of This Metabolite in Vivo

by Marcel Delaforge, Radu C. Duca, Patrick Balaguer, Frederique Bravin
Published 2009-04-01

A Cell Model Suitable for a High-Throughput Screening of Inhibitors of the Wnt/β-Catenin Pathway

by Marina Grimaldi, Marina Grimaldi, Marina Grimaldi, Marina Grimaldi, Abdelhay Boulahtouf, Abdelhay Boulahtouf, Abdelhay Boulahtouf, Abdelhay Boulahtouf, Corinne Prévostel, Corinne Prévostel, Corinne Prévostel, Corinne Prévostel, Alain Thierry, Alain Thierry, Alain Thierry, Alain Thierry, Patrick Balaguer, Patrick Balaguer, Patrick Balaguer, Patrick Balaguer, Philippe Blache, Philippe Blache, Philippe Blache, Philippe Blache
Published 2018-10-01

Manipulating Protein Acetylation in Breast Cancer: A Promising Approach in Combination with Hormonal Therapies?

by Aurélien Linares, Florence Dalenc, Patrick Balaguer, Nathalie Boulle, Vincent Cavailles
Published 2011-01-01

Innovative Bio-Based Organic UV-A and Blue Light Filters from Meldrum’s Acid

by Cédric Peyrot, Matthieu M. Mention, Fanny Brunissen, Patrick Balaguer, Florent Allais
Published 2020-05-01

Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations

by Albane le Maire, Catherine Teyssier, Patrick Balaguer, William Bourguet, Pierre Germain
Published 2019-11-01

Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes.

by Martin Krøyer Rasmussen, Patrick Balaguer, Bo Ekstrand, Martine Daujat-Chavanieu, Sabine Gerbal-Chaloin
Published 2016-01-01

Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: role of PPARalpha, PPARgamma and LXRalpha.

by Jonathan Goldwasser, Pazit Y Cohen, Eric Yang, Patrick Balaguer, Martin L Yarmush, Yaakov Nahmias
Published 2010-08-01

A Comparative Study of Human and Zebrafish Pregnane X Receptor Activities of Pesticides and Steroids Using In Vitro Reporter Gene Assays

by Nicolas Creusot, Clémentine Garoche, Marina Grimaldi, Abdelhay Boulahtouf, Barbara Chiavarina, William Bourguet, Patrick Balaguer
Published 2021-05-01

Preparation of Renewable Epoxy-Amine Resins With Tunable Thermo-Mechanical Properties, Wettability and Degradation Abilities From Lignocellulose- and Plant Oils-Derived Components

by Louis Hollande, Louis Hollande, Izia Do Marcolino, Patrick Balaguer, Sandra Domenek, Richard A. Gross, Florent Allais
Published 2019-03-01

High Content Screening Using New U2OS Reporter Cell Models Identifies Harmol Hydrochloride as a Selective and Competitive Antagonist of the Androgen Receptor

by Hadjer Dellal, Abdelhay Boulahtouf, Elina Alaterre, Alice Cuenant, Marina Grimaldi, William Bourguet, Céline Gongora, Patrick Balaguer, Philippe Pourquier
Published 2020-06-01

Towards symmetry driven and nature inspired UV filter design

by Michael D. Horbury, Emily L. Holt, Louis M. M. Mouterde, Patrick Balaguer, Juan Cebrián, Laurent Blasco, Florent Allais, Vasilios G. Stavros
Published 2019-10-01

Correction: Potential Role of Estrogen Receptor Beta as a Tumor Suppressor of Epithelial Ovarian Cancer

by Carine Bossard, Muriel Busson, David Vindrieux, Françoise Gaudin, Véronique Machelon, Madly Brigitte, Carine Jacquard, Arnaud Pillon, Patrick Balaguer, Karl Balabanian, Gwendal Lazennec
Published 2013-01-01

Characterization of Glyceollins as Novel Aryl Hydrocarbon Receptor Ligands and Their Role in Cell Migration

by Thu Ha Pham, Sylvain Lecomte, Remy Le Guevel, Aurélie Lardenois, Bertrand Evrard, Frédéric Chalmel, François Ferriere, Patrick Balaguer, Theo Efstathiou, Farzad Pakdel
Published 2020-02-01

Potential role of estrogen receptor beta as a tumor suppressor of epithelial ovarian cancer.

by Carine Bossard, Muriel Busson, David Vindrieux, Françoise Gaudin, Véronique Machelon, Madly Brigitte, Carine Jacquard, Arnaud Pillon, Patrick Balaguer, Karl Balabanian, Gwendal Lazennec
Published 2012-01-01

Correction: Potential Role of Estrogen Receptor Beta as a Tumor Suppressor of Epithelial Ovarian Cancer.

by Carine Bossard, Muriel Busson, David Vindrieux, Françoise Gaudin, Véronique Machelon, Madly Brigitte, Carine Jacquard, Arnaud Pillon, Patrick Balaguer, Karl Balabanian, Gwendal Lazennec
Published 2013-01-01

The phytoestrogen genistein affects zebrafish development through two different pathways.

by Sana Sassi-Messai, Yann Gibert, Laure Bernard, Shin-Ichi Nishio, Karine F Ferri Lagneau, José Molina, Monika Andersson-Lendahl, Gérard Benoit, Patrick Balaguer, Vincent Laudet
Published 2009-01-01

The Anti-Cancer Drug Dabrafenib Is a Potent Activator of the Human Pregnane X Receptor

by Nicolas Creusot, Matthieu Gassiot, Elina Alaterre, Barbara Chiavarina, Marina Grimaldi, Abdelhay Boulahtouf, Lucia Toporova, Sabine Gerbal-Chaloin, Martine Daujat-Chavanieu, Alice Matheux, Roger Rahmani, Céline Gongora, Alexandre Evrard, Philippe Pourquier, Patrick Balaguer
Published 2020-07-01

In vitro modulation of multidrug resistance by pregnane steroids and in vivo inhibition of tumour development by 7α-OBz-11α(R)-OTHP-5β-pregnanedione in K562/R7 and H295R cell xenog...

by Ghina Alameh, Agnès Emptoz-Bonneton, Marc Rolland de Ravel, Eva L. Matera, Elisabeth Mappus, Patrick Balaguer, Luc Rocheblave, Thierry Lomberget, Charles Dumontet, Marc Le Borgne, Michel Pugeat, Catherine Grenot, Claude Y. Cuilleron
Published 2019-01-01

PXR Modulates the Prostate Cancer Cell Response to Afatinib by Regulating the Expression of the Monocarboxylate Transporter SLC16A1

by Alice Matheux, Matthieu Gassiot, Gaëlle Fromont, Fanny Leenhardt, Abdelhay Boulahtouf, Eric Fabbrizio, Candice Marchive, Aurélie Garcin, Hanane Agherbi, Eve Combès, Alexandre Evrard, Nadine Houédé, Patrick Balaguer, Céline Gongora, Litaty C. Mbatchi, Philippe Pourquier
Published 2021-07-01