Improved Surface Display of Human Hyal1 and Identification of Testosterone Propionate and Chicoric Acid as New Inhibitors

by Isabelle Lengers, Fabian Herrmann, Marc Le Borgne, Joachim Jose
Published 2020-03-01

Cobalt–Chromium Dental Alloys: Metal Exposures, Toxicological Risks, CMR Classification, and EU Regulatory Framework

by Alina Vaicelyte, Christine Janssen, Marc Le Borgne, Brigitte Grosgogeat
Published 2020-12-01

1st Joint European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC 2015)

by Marc Le Borgne, Samer Haidar, Olivier Duval, Bernhard Wünsch, Joachim Jose
Published 2015-12-01

1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery

by Claire Raingeval, Olivier Cala, Béatrice Brion, Marc Le Borgne, Roderick Eliot Hubbard, Isabelle Krimm
Published 2019-01-01

In Search of Small Molecule Inhibitors Targeting the Flexible CK2 Subunit Interface

by Benoît Bestgen, Zakia Belaid-Choucair, Thierry Lomberget, Marc Le Borgne, Odile Filhol, Claude Cochet
Published 2017-02-01

Behaviour of Tetrabenazine in Acid Medium: Reassessment and Impact on Formulation

by Laurent Ettouati, Zoé Senta-Loys, Sandrine Bourgeois, Bernard Fenet, Marc Le Borgne, Hatem Fessi
Published 2019-01-01

Solubility enhancement of mefenamic acid by inclusion complex with β-cyclodextrin: in silico modelling, formulation, characterisation, and in vitro studies

by Dounia Sid, Milad Baitiche, Zineb Elbahri, Ferhat Djerboua, Mokhtar Boutahala, Zouhair Bouaziz, Marc Le Borgne
Published 2021-01-01

Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining

by Samer Haidar, Zouhair Bouaziz, Christelle Marminon, Tuomo Laitinen, Antti Poso, Marc Le Borgne, Joachim Jose
Published 2017-01-01

Carbazole scaffolds in cancer therapy: a review from 2012 to 2018

by Samar Issa, Anthony Prandina, Nicolas Bedel, Pål Rongved, Saïd Yous, Marc Le Borgne, Zouhair Bouaziz
Published 2019-01-01

Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles

by Anthony Prandina, Lars Herfindal, Sylvie Radix, Pål Rongved, Stein O. Døskeland, Marc Le Borgne, Florent Perret
Published 2018-01-01

Crystal structure of 13-phenyl-2,3,4,13-tetrahydro-1H-indazolo[1,2-b]phthalazine-1,6,11-trione

by Esma Lamera, Saida Benzerka, Abdelmalek Bouraiou, Sofiane Bouacida, Hocine Merazig, Aissa Chibani, Marc Le Borgne, Zouhair Bouaziz
Published 2015-12-01

Biological exploration of a novel 1,2,4-triazole-indole hybrid molecule as antifungal agent

by Fabrice Pagniez, Nicolas Lebouvier, Young Min Na, Isabelle Ourliac-Garnier, Carine Picot, Marc Le Borgne, Patrice Le Pape
Published 2020-01-01

Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-<i>b</i>]indole Derivative, Discovered as CK2 Inhibitor

by Ehab El-Awaad, Robin Birus, Christelle Marminon, Zouhair Bouaziz, Laurens Ballentin, Dagmar Aichele, Marc Le Borgne, Joachim Jose
Published 2021-06-01

Synthesis, X-ray structure, in silico calculation, and carbonic anhydrase inhibitory properties of benzylimidazole metal complexes

by Mehdi Bouchouit, Sofiane Bouacida, Bachir Zouchoune, Hocine Merazig, Silvia Bua, Zouhair Bouaziz, Marc Le Borgne, Claudiu T. Supuran, Abdelmalek Bouraiou
Published 2018-01-01

Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α′...

by Jennifer Hochscherf, Dirk Lindenblatt, Benedict Witulski, Robin Birus, Dagmar Aichele, Christelle Marminon, Zouhair Bouaziz, Marc Le Borgne, Joachim Jose, Karsten Niefind
Published 2017-12-01

Synthesis, Spectroscopic Characterization, and In Vitro Antibacterial Evaluation of Novel Functionalized Sulfamidocarbonyloxyphosphonates

by Abdeslem Bouzina, Khaoula Bechlem, Hajira Berredjem, Billel Belhani, Imène Becheker, Jacques Lebreton, Marc Le Borgne, Zouhair Bouaziz, Christelle Marminon, Malika Berredjem
Published 2018-07-01

Self-Assembled Supramolecular Nanoparticles Improve the Cytotoxic Efficacy of CK2 Inhibitor THN7

by Abdelhamid Nacereddine, Andre Bollacke, Eszter Róka, Christelle Marminon, Zouhair Bouaziz, Ferenc Fenyvesi, Ildikó Katalin Bácskay, Joachim Jose, Florent Perret, Marc Le Borgne
Published 2018-01-01

QSAR Model of Indeno[1,2-<i>b</i>]indole Derivatives and Identification of <i>N</i>-isopentyl-2-methyl-4,9-dioxo-4,9-Dihydronaphtho[2,3-<i>b</i>]furan-3-carboxamide as a Potent CK2...

by Samer Haidar, Christelle Marminon, Dagmar Aichele, Abdelhamid Nacereddine, Wael Zeinyeh, Abdeslem Bouzina, Malika Berredjem, Laurent Ettouati, Zouhair Bouaziz, Marc Le Borgne, Joachim Jose
Published 2019-12-01

Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α′ Structures

by Dirk Lindenblatt, Anna Nickelsen, Violetta M. Applegate, Jennifer Hochscherf, Benedict Witulski, Zouhair Bouaziz, Christelle Marminon, Maria Bretner, Marc Le Borgne, Joachim Jose, Karsten Niefind
Published 2019-03-01

Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds

by Sylwia Bloch, Bożena Nejman-Faleńczyk, Karolina Pierzynowska, Ewa Piotrowska, Alicja Węgrzyn, Christelle Marminon, Zouhair Bouaziz, Pascal Nebois, Joachim Jose, Marc Le Borgne, Luciano Saso, Grzegorz Węgrzyn
Published 2018-01-01