Tumor Necrosis Factor Is a Therapeutic Target for Immunological Unbalance and Cardiac Abnormalities in Chronic Experimental Chagas’ Heart Disease

by Isabela Resende Pereira, Glaucia Vilar-Pereira, Andrea Alice Silva, Otacilio Cruz Moreira, Constança Britto, Ellen Diana Marinho Sarmento, Joseli Lannes-Vieira
Published 2014-01-01

Pentoxifylline reverses chronic experimental Chagasic cardiomyopathy in association with repositioning of abnormal CD8+ T-cell response.

by Isabela Resende Pereira, Glaucia Vilar-Pereira, Otacilio Cruz Moreira, Isalira Peroba Ramos, Daniel Gibaldi, Constança Britto, Milton Ozório Moraes, Joseli Lannes-Vieira
Published 2015-03-01

Comparison and clinical validation of qPCR assays targeting Leishmania 18S rDNA and HSP70 genes in patients with American Tegumentary Leishmaniasis.

by Camila Patricio Braga Filgueira, Otacilio Cruz Moreira, Lilian Motta Cantanhêde, Heloísa Martins Teixeira de Farias, Renato Porrozzi, Constança Britto, Mariana Côrtes Boité, Elisa Cupolillo
Published 2020-10-01

Priming astrocytes with TNF enhances their susceptibility to Trypanosoma cruzi infection and creates a self-sustaining inflammatory milieu

by Andrea Alice Silva, Rafael Rodrigues Silva, Daniel Gibaldi, Rafael Meyer Mariante, Jessica Brandão dos Santos, Isabela Resende Pereira, Otacílio Cruz Moreira, Joseli Lannes-Vieira
Published 2017-09-01

Validation of a novel multiplex real-time PCR assay for Trypanosoma cruzi detection and quantification in açai pulp.

by Paula Finamore-Araujo, Amanda Faier-Pereira, Carlos Ramon do Nascimento Brito, Eldrinei Gomes Peres, Klenicy Kazumy de Lima Yamaguchi, Renata Trotta Barroso Ferreira, Otacilio Cruz Moreira
Published 2021-01-01

Treatment With Suboptimal Dose of Benznidazole Mitigates Immune Response Molecular Pathways in Mice With Chronic Chagas Cardiomyopathy

by Priscila Silva Grijó Farani, Priscila Silva Grijó Farani, Khodeza Begum, Glaucia Vilar-Pereira, Isabela Resende Pereira, Igor C. Almeida, Sourav Roy, Joseli Lannes-Vieira, Otacilio Cruz Moreira
Published 2021-07-01

Memory impairment in chronic experimental Chagas disease: Benznidazole therapy reversed cognitive deficit in association with reduction of parasite load and oxidative stress in the...

by Glaucia Vilar-Pereira, Leda Castaño Barrios, Andrea Alice da Silva, Angelica Martins Batista, Isabela Resende Pereira, Otacílio Cruz Moreira, Constança Britto, Hílton Antônio Mata Dos Santos, Joseli Lannes-Vieira
Published 2021-01-01

A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy.

by Isabela Resende Pereira, Glaucia Vilar-Pereira, Virgínia Marques, Andrea Alice da Silva, Bráulia Caetano, Otacilio Cruz Moreira, Alexandre Vieira Machado, Oscar Bruna-Romero, Maurício Martins Rodrigues, Ricardo Tostes Gazzinelli, Joseli Lannes-Vieira
Published 2015-01-01

Intranasal vaccination with leishmanial antigens protects golden hamsters (Mesocricetus auratus) against Leishmania (Viannia) Braziliensis infection.

by Luzinei da Silva-Couto, Raquel Peralva Ribeiro-Romão, Andrea Franco Saavedra, Beatriz Lilian da Silva Costa Souza, Otacílio Cruz Moreira, Adriano Gomes-Silva, Bartira Rossi-Bergmann, Alda Maria Da-Cruz, Eduardo Fonseca Pinto
Published 2015-01-01

Inducible nitric oxide synthase in heart tissue and nitric oxide in serum of Trypanosoma cruzi-infected rhesus monkeys: association with heart injury.

by Cristiano Marcelo Espinola Carvalho, Jaline Coutinho Silverio, Andrea Alice da Silva, Isabela Resende Pereira, Janice Mery Chicarino Coelho, Constança Carvalho Britto, Otacílio Cruz Moreira, Renato Sergio Marchevsky, Sergio Salles Xavier, Ricardo Tostes Gazzinelli, Maria da Glória Bonecini-Almeida, Joseli Lannes-Vieira
Published 2012-01-01

Effects of Cholinergic Stimulation with Pyridostigmine Bromide on Chronic Chagasic Cardiomyopathic Mice

by Marília Beatriz de Cuba, Marcus Paulo Ribeiro Machado, Thais Soares Farnesi, Angelica Cristina Alves, Livia Alves Martins, Lucas Felipe de Oliveira, Caroline Santos Capitelli, Camila Ferreira Leite, Marcos Vinícius Silva, Juliana Reis Machado, Henrique Borges Kappel, Helioswilton Sales de Campos, Luciano Paiva, Natália Lins da Silva Gomes, Ana Carolina Guimarães Faleiros, Constança Felicia de Paoli de Carvalho Britto, Wilson Savino, Otacílio Cruz Moreira, Virmondes Rodrigues Jr., Nicola Montano, Eliane Lages-Silva, Luis Eduardo Ramirez, Valdo Jose Dias da Silva
Published 2014-01-01