Alzheimer’s and ABC transporters — new opportunities for diagnostics and treatment

by Jens Pahnke, Oliver Langer, Markus Krohn
Published 2014-12-01

Reproducibility of Quantitative Brain Imaging Using a PET-Only and a Combined PET/MR System

by Martin L. Lassen, Otto Muzik, Thomas Beyer, Marcus Hacker, Claes Nøhr Ladefoged, Jacobo Cal-González, Wolfgang Wadsak, Wolfgang Wadsak, Ivo Rausch, Oliver Langer, Oliver Langer, Oliver Langer, Martin Bauer
Published 2017-07-01

Liver Imaging and Hepatobiliary Contrast Media

by Catherine M. Pastor, Oliver Langer, Bernard E. Van Beers
Published 2018-01-01

ABCB1 and ABCG2 Together Limit the Distribution of ABCB1/ABCG2 Substrates to the Human Retina and the ABCG2 Single Nucleotide Polymorphism Q141K (c.421C> A) May Lead to Increased D...

by Myriam El Biali, Rudolf Karch, Cécile Philippe, Helmuth Haslacher, Nicolas Tournier, Marcus Hacker, Markus Zeitlinger, Doreen Schmidl, Oliver Langer, Oliver Langer, Martin Bauer
Published 2021-06-01

Tobacco Smoke and Inhaled Drugs Alter Expression and Activity of Multidrug Resistance-Associated Protein-1 (MRP1) in Human Distal Lung Epithelial Cells in vitro

by Mohammed Ali Selo, Mohammed Ali Selo, Anne-Sophie Delmas, Lisa Springer, Viktoria Zoufal, Viktoria Zoufal, Johannes A. Sake, Caoimhe G. Clerkin, Hanno Huwer, Nicole Schneider-Daum, Claus-Michael Lehr, Claus-Michael Lehr, Sabrina Nickel, Oliver Langer, Oliver Langer, Oliver Langer, Carsten Ehrhardt
Published 2020-09-01

Pitfalls and solutions of the fully-automated radiosynthesis of [11C]metoclopramide

by Verena Pichler, Marius Ozenil, Karsten Bamminger, Chrysoula Vraka, Marcus Hacker, Oliver Langer, Wolfgang Wadsak
Published 2019-12-01

Impact of rifampicin-inhibitable transport on the liver distribution and tissue kinetics of erlotinib assessed with PET imaging in rats

by Dorra Amor, Sébastien Goutal, Solène Marie, Fabien Caillé, Martin Bauer, Oliver Langer, Sylvain Auvity, Nicolas Tournier
Published 2018-08-01

Imaging-Based Characterization of a <i>Slco2b1^(-/-)</i> Mouse Model Using [¹¹C]Erlotinib and [^99mTc]Mebrofenin as Probe Substrates

by Solène Marie, Irene Hernández-Lozano, Louise Breuil, Charles Truillet, Shuiying Hu, Alex Sparreboom, Nicolas Tournier, Oliver Langer
Published 2021-06-01

Assessing the Functional Redundancy between P-gp and BCRP in Controlling the Brain Distribution and Biliary Excretion of Dual Substrates with PET Imaging in Mice

by Irene Hernández-Lozano, Severin Mairinger, Alexander Traxl, Michael Sauberer, Thomas Filip, Johann Stanek, Claudia Kuntner, Thomas Wanek, Oliver Langer
Published 2021-08-01

Validation of Pharmacological Protocols for Targeted Inhibition of Canalicular MRP2 Activity in Hepatocytes Using [^99mTc]mebrofenin Imaging in Rats

by Solène Marie, Irene Hernández-Lozano, Louise Breuil, Wadad Saba, Anthony Novell, Jean-Luc Gennisson, Oliver Langer, Charles Truillet, Nicolas Tournier
Published 2020-05-01

Comparison of fully-automated radiosyntheses of [11C]erlotinib for preclinical and clinical use starting from in target produced [11C]CO2 or [11C]CH4

by Cécile Philippe, Severin Mairinger, Verena Pichler, Johann Stanek, Lukas Nics, Markus Mitterhauser, Marcus Hacker, Thomas Wanek, Oliver Langer, Wolfgang Wadsak
Published 2018-05-01

Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice

by Johannes Steffen, Markus Krohn, Christina Schwitlick, Thomas Brüning, Kristin Paarmann, Claus U. Pietrzik, Henrik Biverstål, Baiba Jansone, Oliver Langer, Jens Pahnke
Published 2017-06-01

Brain Distribution of Dual ABCB1/ABCG2 Substrates Is Unaltered in a Beta-Amyloidosis Mouse Model

by Thomas Wanek, Viktoria Zoufal, Mirjam Brackhan, Markus Krohn, Severin Mairinger, Thomas Filip, Michael Sauberer, Johann Stanek, Thomas Pekar, Jens Pahnke, Oliver Langer
Published 2020-11-01

EGFR is required for FOS‐dependent bone tumor development via RSK2/CREB signaling

by Markus Linder, Elisabeth Glitzner, Sriram Srivatsa, Latifa Bakiri, Kazuhiko Matsuoka, Parastoo Shahrouzi, Monika Dumanic, Philipp Novoszel, Thomas Mohr, Oliver Langer, Thomas Wanek, Markus Mitterhauser, Erwin F Wagner, Maria Sibilia
Published 2018-11-01

Assessment of brain delivery of a model ABCB1/ABCG2 substrate in patients with non-contrast-enhancing brain tumors with positron emission tomography

by Beatrix Wulkersdorfer, Martin Bauer, Rudolf Karch, Harald Stefanits, Cécile Philippe, Maria Weber, Thomas Czech, Marie-Claude Menet, Xavier Declèves, Johannes A. Hainfellner, Matthias Preusser, Marcus Hacker, Markus Zeitlinger, Markus Müller, Oliver Langer
Published 2019-12-01