Mice are not Men: ADAM30 Findings Emphasize a Broader Look Towards Murine Alzheimer's Disease Models

by Christoph Becker-Pauly, Claus U. Pietrzik
Published 2016-07-01

Brain endothelial LRP1 maintains blood–brain barrier integrity

by Steffen E. Storck, Magdalena Kurtyka, Claus U. Pietrzik
Published 2021-06-01

Presenilin is the molecular target of acidic γ-secretase modulators in living cells.

by Thorsten Jumpertz, Andreas Rennhack, Julia Ness, Sandra Baches, Claus U Pietrzik, Bruno Bulic, Sascha Weggen
Published 2012-01-01

LRP1 modulates APP trafficking along early compartments of the secretory pathway

by Elaine Waldron, Catherine Heilig, Andrea Schweitzer, Nirupa Nadella, Sebastian Jaeger, Anne M. Martin, Sascha Weggen, Klaudia Brix, Claus U. Pietrzik
Published 2008-08-01

Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice

by Johannes Steffen, Markus Krohn, Christina Schwitlick, Thomas Brüning, Kristin Paarmann, Claus U. Pietrzik, Henrik Biverstål, Baiba Jansone, Oliver Langer, Jens Pahnke
Published 2017-06-01

Uptake mechanism of ApoE-modified nanoparticles on brain capillary endothelial cells as a blood-brain barrier model.

by Sylvia Wagner, Anja Zensi, Sascha L Wien, Sabrina E Tschickardt, Wladislaw Maier, Tikva Vogel, Franz Worek, Claus U Pietrzik, Jörg Kreuter, Hagen von Briesen
Published 2012-01-01

Is LRP2 Involved in Leptin Transport over the Blood-Brain Barrier and Development of Obesity?

by Elvira S. Sandin, Julica Folberth, Helge Müller-Fielitz, Claus U. Pietrzik, Elisabeth Herold, Thomas E. Willnow, Paul T. Pfluger, Ruben Nogueiras, Vincent Prevot, Thomas Krey, Markus Schwaninger
Published 2021-05-01

LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State

by Claus U. Pietrzik, Stefan Kins, Uta-Mareike Herr, Paul Strecker, Steffen E. Storck, Carolin Thomas, Verena Rabiej, Anne Junker, Sandra Schilling, Nadine Schmidt, C. Marie Dowds, Simone Eggert
Published 2017-04-01

The LepR-mediated leptin transport across brain barriers controls food reward

by Alessandro Di Spiezio, Elvira Sonia Sandin, Riccardo Dore, Helge Müller-Fielitz, Steffen E. Storck, Mareike Bernau, Walter Mier, Henrik Oster, Olaf Jöhren, Claus U. Pietrzik, Hendrik Lehnert, Markus Schwaninger
Published 2018-02-01