Gene Augmentation and Editing to Improve TCR Engineered T Cell Therapy against Solid Tumors

by Vania Lo Presti, Frank Buitenwerf, Niek P. van Til, Stefan Nierkens
Published 2020-12-01

Strategies to Genetically Modulate Dendritic Cells to Potentiate Anti-Tumor Responses in Hematologic Malignancies

by Annelisa M. Cornel, Niek P. van Til, Jaap Jan Boelens, Jaap Jan Boelens, Jaap Jan Boelens, Stefan Nierkens
Published 2018-05-01

Efficient lentiviral transduction method to gene modify cord blood CD8+ T cells for cancer therapy applications

by Vania Lo Presti, Annelisa M. Cornel, Maud Plantinga, Ester Dünnebach, Jurgen Kuball, Jaap Jan Boelens, Stefan Nierkens, Niek P. van Til
Published 2021-06-01

Transplantation, gene therapy and intestinal pathology in MNGIE patients and mice

by Rana Yadak, Max V. Boot, Niek P. van Til, Dominique Cazals-Hatem, Armin Finkenstedt, Elly Bogaerts, Irenaeus F. de Coo, Marianna Bugiani
Published 2018-10-01

Angiopoietin-like protein 3 promotes preservation of stemness during ex vivo expansion of murine hematopoietic stem cells.

by Elnaz Farahbakhshian, Monique M Verstegen, Trudi P Visser, Sima Kheradmandkia, Dirk Geerts, Shazia Arshad, Noveen Riaz, Frank Grosveld, Niek P van Til, Jules P P Meijerink
Published 2014-01-01

Lentiviral Hematopoietic Stem Cell Gene Therapy Corrects Murine Pompe Disease

by Merel Stok, Helen de Boer, Marshall W. Huston, Edwin H. Jacobs, Onno Roovers, Trudi P. Visser, Holger Jahr, Dirk J. Duncker, Elza D. van Deel, Arnold J.J. Reuser, Niek P. van Til, Gerard Wagemaker
Published 2020-06-01

Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of MNGIE

by Rana Yadak, Raquel Cabrera-Pérez, Javier Torres-Torronteras, Marianna Bugiani, Joost C. Haeck, Marshall W. Huston, Elly Bogaerts, Steffi Goffart, Edwin H. Jacobs, Merel Stok, Lorena Leonardelli, Luca Biasco, Robert M. Verdijk, Monique R. Bernsen, George Ruijter, Ramon Martí, Gerard Wagemaker, Niek P. van Til, Irenaeus F.M. de Coo
Published 2018-03-01