Twist and Turn—Topoisomerase Functions in Mitochondrial DNA Maintenance

by Steffi Goffart, Anu Hangas, Jaakko L. O. Pohjoismäki
Published 2019-04-01

TFAM knockdown-triggered mtDNA-nucleoid aggregation and a decrease in mtDNA copy number induce the reorganization of nucleoid populations and mitochondria-associated ER-membrane co...

by Koit Aasumets, Yuliya Basikhina, Jaakko L. Pohjoismäki, Steffi Goffart, Joachim Gerhold
Published 2021-12-01

The Type and Source of Reactive Oxygen Species Influences the Outcome of Oxidative Stress in Cultured Cells

by Steffi Goffart, Petra Tikkanen, Craig Michell, Trevor Wilson, Jaakko L. O. L. O. Pohjoismäki
Published 2021-04-01

Developmental and pathological changes in the human cardiac muscle mitochondrial DNA organization, replication and copy number.

by Jaakko L O Pohjoismäki, Steffi Goffart, Robert W Taylor, Douglas M Turnbull, Anu Suomalainen, Howard T Jacobs, Pekka J Karhunen
Published 2010-05-01

Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of MNGIE

by Rana Yadak, Raquel Cabrera-Pérez, Javier Torres-Torronteras, Marianna Bugiani, Joost C. Haeck, Marshall W. Huston, Elly Bogaerts, Steffi Goffart, Edwin H. Jacobs, Merel Stok, Lorena Leonardelli, Luca Biasco, Robert M. Verdijk, Monique R. Bernsen, George Ruijter, Ramon Martí, Gerard Wagemaker, Niek P. van Til, Irenaeus F.M. de Coo
Published 2018-03-01