Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer’s Disease

by Qi Guo, Eric B. Dammer, Eric B. Dammer, Maotian Zhou, Sean R. Kundinger, Marla Gearing, Marla Gearing, James J. Lah, James J. Lah, Allan I. Levey, Allan I. Levey, Joshua M. Shulman, Joshua M. Shulman, Nicholas T. Seyfried, Nicholas T. Seyfried, Nicholas T. Seyfried
Published 2021-03-01

A network approach reveals driver genes associated with survival of patients with triple-negative breast cancer

by Courtney D. Dill, Eric B. Dammer, Ti'ara L. Griffen, Nicholas T. Seyfried, James W. Lillard, Jr.
Published 2021-05-01

Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease

by Jingting Dai, Jingting Dai, Jingting Dai, Jingting Dai, Erik C. B. Johnson, Erik C. B. Johnson, Eric B. Dammer, Duc M. Duong, Duc M. Duong, Marla Gearing, Marla Gearing, James J. Lah, James J. Lah, Allan I. Levey, Allan I. Levey, Thomas S. Wingo, Thomas S. Wingo, Thomas S. Wingo, Thomas S. Wingo, Nicholas T. Seyfried, Nicholas T. Seyfried, Nicholas T. Seyfried
Published 2018-12-01

Correction to: Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer’s disease

by Laura E. Donovan, Eric B. Dammer, Duc M. Duong, John J. Hanfelt, Allan I. Levey, Nicholas T. Seyfried, James J. Lah
Published 2021-05-01

Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer’s Disease

by Lenora Higginbotham, Eric B. Dammer, Duc M. Duong, Erica Modeste, Thomas J. Montine, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
Published 2019-08-01

Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes—Activation and Age-Related Effects

by Srikant Rangaraju, Syed Ali Raza, Noel Xiang’An Li, Ranjita Betarbet, Eric B. Dammer, Duc Duong, James J. Lah, Nicholas T. Seyfried, Allan I. Levey
Published 2018-03-01

A proteomic network approach across the ALS‐FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain

by Mfon E Umoh, Eric B Dammer, Jingting Dai, Duc M Duong, James J Lah, Allan I Levey, Marla Gearing, Jonathan D Glass, Nicholas T Seyfried
Published 2018-01-01

Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease

by Erik C. B. Johnson, Eric B. Dammer, Duc M. Duong, Luming Yin, Madhav Thambisetty, Juan C. Troncoso, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
Published 2018-10-01

Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations

by Meixiang Huang, Erica Modeste, Eric Dammer, Paola Merino, Georgia Taylor, Duc M. Duong, Qiudong Deng, Christopher J. Holler, Marla Gearing, Dennis Dickson, Nicholas T. Seyfried, Thomas Kukar
Published 2020-10-01

Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

by Srikant Rangaraju, Eric B. Dammer, Syed Ali Raza, Priyadharshini Rathakrishnan, Hailian Xiao, Tianwen Gao, Duc M. Duong, Michael W. Pennington, James J. Lah, Nicholas T. Seyfried, Allan I. Levey
Published 2018-05-01

Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.

by Eric B Dammer, Claudia Fallini, Yair M Gozal, Duc M Duong, Wilfried Rossoll, Ping Xu, James J Lah, Allan I Levey, Junmin Peng, Gary J Bassell, Nicholas T Seyfried
Published 2012-01-01

Integrated analysis of the aging brain transcriptome and proteome in tauopathy

by Carl Grant Mangleburg, Timothy Wu, Hari K. Yalamanchili, Caiwei Guo, Yi-Chen Hsieh, Duc M. Duong, Eric B. Dammer, Philip L. De Jager, Nicholas T. Seyfried, Zhandong Liu, Joshua M. Shulman
Published 2020-09-01

A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation

by Srikant Rangaraju, Syed Ali Raza, Andrea Pennati, Qiudong Deng, Eric B. Dammer, Duc Duong, Michael W. Pennington, Malu G. Tansey, James J. Lah, Ranjita Betarbet, Nicholas T. Seyfried, Allan I. Levey
Published 2017-06-01

Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer’s disease-related proteins

by Srikant Rangaraju, Eric B. Dammer, Syed Ali Raza, Tianwen Gao, Hailian Xiao, Ranjita Betarbet, Duc M. Duong, James A. Webster, Chadwick M. Hales, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
Published 2018-06-01

Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer’s disease

by Kamil Borkowski, Theresa L. Pedersen, Nicholas T. Seyfried, James J. Lah, Allan I. Levey, Chadwick M. Hales, Eric B. Dammer, Colette Blach, Gregory Louie, Rima Kaddurah-Daouk, John W. Newman, Alzheimer’s Disease Metabolomics Consortium
Published 2021-09-01

A proteomic network approach resolves stage-specific molecular phenotypes in chronic traumatic encephalopathy

by Laura Gutierrez-Quiceno, Eric B. Dammer, Ashlyn Grace Johnson, James A. Webster, Rhythm Shah, Duc Duong, Luming Yin, Nicholas T. Seyfried, Victor E. Alvarez, Thor D. Stein, Ann C. McKee, Chadwick M. Hales
Published 2021-06-01

Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer’s disease

by Sruti Rayaprolu, Tianwen Gao, Hailian Xiao, Supriya Ramesha, Laura D. Weinstock, Jheel Shah, Duc M. Duong, Eric B. Dammer, James A. Webster, James J. Lah, Levi B. Wood, Ranjita Betarbet, Allan I. Levey, Nicholas T. Seyfried, Srikant Rangaraju
Published 2020-05-01

Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease

by Yi-Chen Hsieh, Caiwei Guo, Hari K. Yalamanchili, Measho Abreha, Rami Al-Ouran, Yarong Li, Eric B. Dammer, James J. Lah, Allan I. Levey, David A. Bennett, Philip L. De Jager, Nicholas T. Seyfried, Zhandong Liu, Joshua M. Shulman
Published 2019-10-01

A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with <i>NTNG1</i> and CNOT3

by Selina M. Vattathil, Yue Liu, Nadia V. Harerimana, Adriana Lori, Ekaterina S. Gerasimov, Thomas G. Beach, Eric M. Reiman, Philip L. De Jager, Julie A. Schneider, David A. Bennett, Nicholas T. Seyfried, Allan I. Levey, Aliza P. Wingo, Thomas S. Wingo
Published 2021-05-01

Proteomic Analysis of Human Immune Responses to Live-Attenuated Tularemia Vaccine

by Yie-Hwa Chang, Duc M. Duong, Johannes B. Goll, David C. Wood, Travis L. Jensen, Luming Yin, Casey E. Gelber, Nicholas T. Seyfried, Evan Anderson, Muktha S. Natrajan, Nadine Rouphael, Robert A. Johnson, Patrick Sanz, Mark J. Mulligan, Daniel F. Hoft
Published 2020-07-01