The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT inhibitor MK2206 in LKB1-dependent manner.

by Jieru Meng, Mourad Majidi, Bingliang Fang, Lin Ji, B Nebiyou Bekele, John D Minna, Jack A Roth
Published 2013-01-01

Exogenous Restoration of TUSC2 Expression Induces Responsiveness to Erlotinib in Wildtype Epidermal Growth Factor Receptor (EGFR) Lung Cancer Cells through Context Specific Pathway...

by Bingbing Dai, Shaoyu Yan, Humberto Lara-Guerra, Hiroyuki Kawashima, Ryo Sakai, Gitanjali Jayachandran, Mourad Majidi, Reza Mehran, Jing Wang, B Nebiyou Bekele, Veerabhadran Baladandayuthapani, Suk-Young Yoo, Ying Wang, Jun Ying, Feng Meng, Lin Ji, Jack A Roth
Published 2015-01-01