Protein Tyrosine Phosphatases: Regulators of CD4 T Cells in Inflammatory Bowel Disease

by Kelly A. Pike, Kelly A. Pike, Michel L. Tremblay, Michel L. Tremblay, Michel L. Tremblay, Michel L. Tremblay
Published 2018-10-01

Protein tyrosine phosphatases, TC-PTP, SHP1, and SHP2, cooperate in rapid dephosphorylation of Stat3 in keratinocytes following UVB irradiation.

by Dae Joon Kim, Michel L Tremblay, John Digiovanni
Published 2010-04-01

Insufficient milk supply and breast cancer risk: a systematic review.

by Jacqueline M Cohen, Jennifer A Hutcheon, Sofi G Julien, Michel L Tremblay, Rebecca Fuhrer
Published 2009-12-01

Increased susceptibility to dextran sulfate sodium induced colitis in the T cell protein tyrosine phosphatase heterozygous mouse.

by Syed-Wajahat Hassan, Karen M Doody, Serge Hardy, Noriko Uetani, Denis Cournoyer, Michel L Tremblay
Published 2010-01-01

Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain.

by Chia-Lun Wu, Serge Hardy, Isabelle Aubry, Melissa Landry, Allison Haggarty, Horacio Uri Saragovi, Michel L Tremblay
Published 2017-01-01

HD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain.

by Marie-Claude Gingras, Yu Ling Zhang, Dmitri Kharitidi, Alastair J Barr, Stefan Knapp, Michel L Tremblay, Arnim Pause
Published 2009-01-01

Deletion of Protein Tyrosine Phosphatase 1B (PTP1B) Enhances Endothelial Cyclooxygenase 2 Expression and Protects Mice from Type 1 Diabetes-Induced Endothelial Dysfunction.

by David J Herren, J Blake Norman, Ruchi Anderson, Michel L Tremblay, Anne-Cecile Huby, Eric J Belin de Chantemèle
Published 2015-01-01

PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils.

by Lei Yue, Min Yan, Michel L Tremblay, Tong-Jun Lin, Hua Li, Ting Yang, Xia Song, Tianhong Xie, Zhongping Xie
Published 2019-01-01

Downregulation of PTP1B and TC-PTP phosphatases potentiate dendritic cell-based immunotherapy through IL-12/IFNγ signaling

by Claudia Penafuerte, Matthew Feldhammer, John R. Mills, Valerie Vinette, Kelly A. Pike, Anita Hall, Eva Migon, Gerard Karsenty, Jerry Pelletier, George Zogopoulos, Michel L. Tremblay
Published 2017-06-01

Strain-dependent differences in bone development, myeloid hyperplasia, morbidity and mortality in ptpn2-deficient mice.

by Florian Wiede, Sock Hui Chew, Catherine van Vliet, Ingrid J Poulton, Konstantinos Kyparissoudis, Tedjo Sasmono, Kim Loh, Michel L Tremblay, Dale I Godfrey, Natalie A Sims, Tony Tiganis
Published 2012-01-01

Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol.

by Regina Cencic, Marilyn Carrier, Gabriela Galicia-Vázquez, Marie-Eve Bordeleau, Rami Sukarieh, Annie Bourdeau, Brigitte Brem, Jose G Teodoro, Harald Greger, Michel L Tremblay, John A Porco, Jerry Pelletier
Published 2009-01-01

ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer

by Geneviève Deblois, Harvey W. Smith, Ingrid S. Tam, Simon-Pierre Gravel, Maxime Caron, Paul Savage, David P. Labbé, Louis R. Bégin, Michel L. Tremblay, Morag Park, Guillaume Bourque, Julie St-Pierre, William J. Muller, Vincent Giguère
Published 2016-07-01

Ablation of the Sam68 RNA binding protein protects mice from age-related bone loss.

by Stéphane Richard, Nazi Torabi, Gladys Valverde Franco, Guy A Tremblay, Taiping Chen, Gillian Vogel, Mélanie Morel, Patrick Cléroux, Alexandre Forget-Richard, Svetlana Komarova, Michel L Tremblay, Wei Li, Ailian Li, Yun Jing Gao, Janet E Henderson
Published 2005-12-01

The autoimmune susceptibility gene, PTPN2, restricts expansion of a novel mouse adherent-invasive E. coli

by Ali Shawki, Rocio Ramirez, Marianne R. Spalinger, Paul M. Ruegger, Anica Sayoc-Becerra, Alina N. Santos, Pritha Chatterjee, Vinicius Canale, Jonathan D. Mitchell, John C. Macbeth, Casey M. Gries, Michel L. Tremblay, Ansel Hsiao, James Borneman, Declan F. McCole
Published 2020-11-01