Pore mutation N617D in the skeletal muscle DHPR blocks Ca2+ influx due to atypical high-affinity Ca2+ binding

by Anamika Dayal, Monica L Fernández-Quintero, Klaus R Liedl, Manfred Grabner
Published 2021-06-01

pH-Induced Local Unfolding of the Phl p 6 Pollen Allergen From cpH-MD

by Florian Hofer, Anna S. Kamenik, Monica L. Fernández-Quintero, Johannes Kraml, Klaus R. Liedl
Published 2021-01-01

Transitions of CDR-L3 Loop Canonical Cluster Conformations on the Micro-to-Millisecond Timescale

by Monica L. Fernández-Quintero, Barbara A. Math, Johannes R. Loeffler, Klaus R. Liedl
Published 2019-11-01

Shark Antibody Variable Domains Rigidify Upon Affinity Maturation—Understanding the Potential of Shark Immunoglobulins as Therapeutics

by Monica L. Fernández-Quintero, Clarissa A. Seidler, Patrick K. Quoika, Klaus R. Liedl
Published 2021-04-01

Mutation of Framework Residue H71 Results in Different Antibody Paratope States in Solution

by Monica L. Fernández-Quintero, Katharina B. Kroell, Florian Hofer, Jakob R. Riccabona, Klaus R. Liedl
Published 2021-03-01

T-Cell Receptor CDR3 Loop Conformations in Solution Shift the Relative Vα-Vβ Domain Distributions

by Monica L. Fernández-Quintero, Nancy D. Pomarici, Johannes R. Loeffler, Clarissa A. Seidler, Klaus R. Liedl
Published 2020-07-01

Characterizing the Diversity of the CDR-H3 Loop Conformational Ensembles in Relationship to Antibody Binding Properties

by Monica L. Fernández-Quintero, Johannes R. Loeffler, Johannes Kraml, Ursula Kahler, Anna S. Kamenik, Klaus R. Liedl
Published 2019-01-01

Structural determinants of voltage-gating properties in calcium channels

by Monica L Fernández-Quintero, Yousra El Ghaleb, Petronel Tuluc, Marta Campiglio, Klaus R Liedl, Bernhard E Flucher
Published 2021-03-01

Local and Global Rigidification Upon Antibody Affinity Maturation

by Monica L. Fernández-Quintero, Johannes R. Loeffler, Lisa M. Bacher, Franz Waibl, Clarissa A. Seidler, Klaus R. Liedl
Published 2020-08-01

Conformational Shifts of Stacked Heteroaromatics: Vacuum vs. Water Studied by Machine Learning

by Johannes R. Loeffler, Monica L. Fernández-Quintero, Franz Waibl, Patrick K. Quoika, Florian Hofer, Michael Schauperl, Klaus R. Liedl
Published 2021-03-01

Germline-Dependent Antibody Paratope States and Pairing Specific VH-VL Interface Dynamics

by Monica L. Fernández-Quintero, Katharina B. Kroell, Lisa M. Bacher, Johannes R. Loeffler, Patrick K. Quoika, Guy Georges, Alexander Bujotzek, Hubert Kettenberger, Klaus R. Liedl
Published 2021-08-01

Surprisingly Fast Interface and Elbow Angle Dynamics of Antigen-Binding Fragments

by Monica L. Fernández-Quintero, Katharina B. Kroell, Martin C. Heiss, Johannes R. Loeffler, Patrick K. Quoika, Franz Waibl, Alexander Bujotzek, Ekkehard Moessner, Guy Georges, Klaus R. Liedl
Published 2020-11-01