Shark Antibody Variable Domains Rigidify Upon Affinity Maturation—Understanding the Potential of Shark Immunoglobulins as Therapeutics

by Monica L. Fernández-Quintero, Clarissa A. Seidler, Patrick K. Quoika, Klaus R. Liedl
Published 2021-04-01

Conformational Shifts of Stacked Heteroaromatics: Vacuum vs. Water Studied by Machine Learning

by Johannes R. Loeffler, Monica L. Fernández-Quintero, Franz Waibl, Patrick K. Quoika, Florian Hofer, Michael Schauperl, Klaus R. Liedl
Published 2021-03-01

Germline-Dependent Antibody Paratope States and Pairing Specific VH-VL Interface Dynamics

by Monica L. Fernández-Quintero, Katharina B. Kroell, Lisa M. Bacher, Johannes R. Loeffler, Patrick K. Quoika, Guy Georges, Alexander Bujotzek, Hubert Kettenberger, Klaus R. Liedl
Published 2021-08-01

Surprisingly Fast Interface and Elbow Angle Dynamics of Antigen-Binding Fragments

by Monica L. Fernández-Quintero, Katharina B. Kroell, Martin C. Heiss, Johannes R. Loeffler, Patrick K. Quoika, Franz Waibl, Alexander Bujotzek, Ekkehard Moessner, Guy Georges, Klaus R. Liedl
Published 2020-11-01