The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages.

by Marc Daigneault, Julie A Preston, Helen M Marriott, Moira K B Whyte, David H Dockrell
Published 2010-01-01

The molecular controls of resolution of inflammation: what can we learn from zebrafish?

by Stephen. A. Renshaw, Catherine. A. Loynes, Daniel. M. Trushell, Philip. W. Ingham, Moira. K. B. Whyte
Published 2006-12-01

Effective caspase inhibition blocks neutrophil apoptosis and reveals Mcl-1 as both a regulator and a target of neutrophil caspase activation.

by David J Wardle, Joseph Burgon, Ian Sabroe, Colin D Bingle, Moira K B Whyte, Stephen A Renshaw
Published 2011-01-01

Regulation of neutrophil senescence by microRNAs.

by Jon R Ward, Paul R Heath, James W Catto, Moira K B Whyte, Marta Milo, Stephen A Renshaw
Published 2011-01-01

Staphylococcus aureus induces eosinophil cell death mediated by α-hemolysin.

by Lynne R Prince, Kirstie J Graham, John Connolly, Sadia Anwar, Robert Ridley, Ian Sabroe, Simon J Foster, Moira K B Whyte
Published 2012-01-01

Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo [version 1; referees: 2 approved, 1 approved with...

by Rebecca S. Dickinson, Fiona Murphy, Catherine Doherty, Sam Williams, Ananda Mirchandani, Joseph Willson, John S. Scotti, Gail Preston, Christopher J. Schofield, Moira K.B. Whyte, Sarah R. Walmsley
Published 2017-10-01

Drift-Diffusion Analysis of Neutrophil Migration during Inflammation Resolution in a Zebrafish Model

by Geoffrey R. Holmes, Giles Dixon, Sean R. Anderson, Constantino Carlos Reyes-Aldasoro, Philip M. Elks, Stephen A. Billings, Moira K. B. Whyte, Visakan Kadirkamanathan, Stephen A. Renshaw
Published 2012-01-01

A cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci.

by Martin A Bewley, Helen M Marriott, Calogero Tulone, Sheila E Francis, Timothy J Mitchell, Robert C Read, Benny Chain, Guido Kroemer, Moira K B Whyte, David H Dockrell
Published 2011-01-01

Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection.

by Marc Daigneault, Thushan I De Silva, Martin A Bewley, Julie A Preston, Helen M Marriott, Andrea M Mitchell, Timothy J Mitchell, Robert C Read, Moira K B Whyte, David H Dockrell
Published 2012-01-01

Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD.

by Martin A Bewley, Kylie B R Belchamber, Kirandeep K Chana, Richard C Budd, Gavin Donaldson, Jadwiga A Wedzicha, Christopher E Brightling, Iain Kilty, Louise E Donnelly, Peter J Barnes, Dave Singh, Moira K B Whyte, David H Dockrell, COPDMAP
Published 2016-01-01

Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen

by Anne L. Robertson, Nikolay V. Ogryzko, Katherine M. Henry, Catherine A. Loynes, Matthew J. Foulkes, Marco M. Meloni, Xingang Wang, Christopher Ford, Malcolm Jackson, Philip W. Ingham, Heather L. Wilson, Stuart N. Farrow, Roberto Solari, Roderick J. Flower, Simon Jones, Moira K. B. Whyte, Stephen A. Renshaw
Published 2016-06-01

A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

by Nadine D. Arnold, Josephine A. Pickworth, Laura E. West, Sarah Dawson, Joana A. Carvalho, Helen Casbolt, Adam T. Braithwaite, James Iremonger, Lewis Renshall, Volker Germaschewski, Matthew McCourt, Philip Bland-Ward, Hager Kowash, Abdul G. Hameed, Alexander M. K. Rothman, Maria G. Frid, A. A. Roger Thompson, Holly R. Evans, Mark Southwood, Nicholas W. Morrell, David C. Crossman, Moira K. B. Whyte, Kurt R. Stenmark, Christopher M. Newman, David G. Kiely, Sheila E. Francis, Allan Lawrie
Published 2019-11-01

­­­­­­­A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS­­­ [version 1; peer review: 1 approved, 3 approved with reservations]...

by Leila Reyes, Manuel A. Sanchez-Garcia, Tyler Morrison, Andy J. M. Howden, Emily R. Watts, Simone Arienti, Pranvera Sadiku, Patricia Coelho, Ananda S. Mirchandani, Ailiang Zhang, David Hope, Sarah K. Clark, Jo Singleton, Shonna Johnston, Robert Grecian, Azin Poon, Sarah McNamara, Isla Harper, Max Head Fourman, Alejandro J. Brenes, Shalini Pathak, Amy Lloyd, Giovanny Rodriguez Blanco, Alex von Kriegsheim, Bart Ghesquiere, Wesley Vermaelen, Camila T. Cologna, Kevin Dhaliwal, Nik Hirani, David H. Dockrell, Moira K. B. Whyte, David Griffith, Doreen A. Cantrell, Sarah R. Walmsley
Published 2021-02-01

­­­­­­­A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS­­­ [version 2; peer review: 1 approved, 3 approved with reservations]...

by Leila Reyes, Manuel A. Sanchez-Garcia, Tyler Morrison, Andy J. M. Howden, Emily R. Watts, Simone Arienti, Pranvera Sadiku, Patricia Coelho, Ananda S. Mirchandani, Ailiang Zhang, David Hope, Sarah K. Clark, Jo Singleton, Shonna Johnston, Robert Grecian, Azin Poon, Sarah McNamara, Isla Harper, Max Head Fourman, Alejandro J. Brenes, Shalini Pathak, Amy Lloyd, Giovanny Rodriguez Blanco, Alex von Kriegsheim, Bart Ghesquiere, Wesley Vermaelen, Camila T. Cologna, Kevin Dhaliwal, Nik Hirani, David H. Dockrell, Moira K. B. Whyte, David Griffith, Doreen A. Cantrell, Sarah R. Walmsley
Published 2021-05-01