Differential IL-1 signaling induced by BMPR2 deficiency drives pulmonary vascular remodeling

by Josephine Pickworth, Alexander Rothman, James Iremonger, Helen Casbolt, Kay Hopkinson, Peter M. Hickey, Santhi Gladson, Sheila Shay, Nicholas W. Morrell, Sheila E. Francis, James D. West, Allan Lawrie
Published 2017-09-01

Selective improvement of pulmonary arterial hypertension with a dual ET/ET receptors antagonist in the apolipoprotein E model of PAH and atherosclerosis

by Lewis Renshall, Nadine Arnold, Laura West, Adam Braithwaite, Josephine Pickworth, Rachel Walker, Mabruka Alfaidi, Janet Chamberlain, Helen Casbolt, A.A. Roger Thompson, Cathy Holt, Marc Iglarz, Sheila Francis, Allan Lawrie
Published 2018-01-01

A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

by Nadine D. Arnold, Josephine A. Pickworth, Laura E. West, Sarah Dawson, Joana A. Carvalho, Helen Casbolt, Adam T. Braithwaite, James Iremonger, Lewis Renshall, Volker Germaschewski, Matthew McCourt, Philip Bland-Ward, Hager Kowash, Abdul G. Hameed, Alexander M. K. Rothman, Maria G. Frid, A. A. Roger Thompson, Holly R. Evans, Mark Southwood, Nicholas W. Morrell, David C. Crossman, Moira K. B. Whyte, Kurt R. Stenmark, Christopher M. Newman, David G. Kiely, Sheila E. Francis, Allan Lawrie
Published 2019-11-01