Lymph Node Cellular and Viral Dynamics in Natural Hosts and Impact for HIV Cure Strategies

by Nicolas Huot, Nicolas Huot, Steven E. Bosinger, Steven E. Bosinger, Mirko Paiardini, R. Keith Reeves, R. Keith Reeves, Michaela Müller-Trutwin, Michaela Müller-Trutwin
Published 2018-04-01

The biased nucleotide composition of HIV-1 triggers type I interferon response and correlates with subtype D increased pathogenicity.

by Nicolas Vabret, Marc Bailly-Bechet, Valérie Najburg, Michaela Müller-Trutwin, Bernard Verrier, Frédéric Tangy
Published 2012-01-01

Interests of the Non-Human Primate Models for HIV Cure Research

by Gauthier Terrade, Nicolas Huot, Caroline Petitdemange, Marie Lazzerini, Aurelio Orta Resendiz, Beatrice Jacquelin, Michaela Müller-Trutwin
Published 2021-08-01

NK-B cell cross talk induces CXCR5 expression on natural killer cells

by Philippe Rascle, Béatrice Jacquelin, Caroline Petitdemange, Vanessa Contreras, Cyril Planchais, Marie Lazzerini, Nathalie Dereuddre-Bosquet, Roger Le Grand, Hugo Mouquet, Nicolas Huot, Michaela Müller-Trutwin
Published 2021-10-01

Non-human Primate Determinants of Natural Killer Cells in Tissues at Steady-State and During Simian Immunodeficiency Virus Infection

by Nicolas Huot, Philippe Rascle, Philippe Rascle, Caroline Petitdemange, Vanessa Contreras, Jean-Louis Palgen, Christiane Stahl-Hennig, Roger Le Grand, Anne-Sophie Beignon, Beatrice Jacquelin, Michaela Müller-Trutwin
Published 2020-09-01

Endogenous TRIM5α Function Is Regulated by SUMOylation and Nuclear Sequestration for Efficient Innate Sensing in Dendritic Cells

by Débora M. Portilho, Juliette Fernandez, Mathieu Ringeard, Anthony K. Machado, Aude Boulay, Martha Mayer, Michaela Müller-Trutwin, Anne-Sophie Beignon, Frank Kirchhoff, Sébastien Nisole, Nathalie J. Arhel
Published 2016-01-01

Role of NKG2a/c+CD8+ T cells in pathogenic versus non-pathogenic SIV infections

by Nicolas Huot, Philippe Rascle, Nicolas Tchitchek, Benedikt Wimmer, Caroline Passaes, Vanessa Contreras, Delphine Desjardins, Christiane Stahl-Hennig, Roger Le Grand, Asier Saez-Cirion, Beatrice Jacquelin, Michaela Müller-Trutwin
Published 2021-04-01

Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection.

by Anne-Sophie Liovat, Marie-Anne Rey-Cuillé, Camille Lécuroux, Béatrice Jacquelin, Isabelle Girault, Gaël Petitjean, Yasmine Zitoun, Alain Venet, Françoise Barré-Sinoussi, Pierre Lebon, Laurence Meyer, Martine Sinet, Michaela Müller-Trutwin
Published 2012-01-01

Impact of early cART on HIV blood and semen compartments at the time of primary infection.

by Antoine Chéret, Christine Durier, Adeline Mélard, Mickaël Ploquin, Julia Heitzmann, Camille Lécuroux, Véronique Avettand-Fenoël, Ludivine David, Gilles Pialoux, Jean-Marie Chennebault, Michaela Müller-Trutwin, Cécile Goujard, Christine Rouzioux, Laurence Meyer, ANRS OPTIPRIM study group
Published 2017-01-01

Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection.

by Béatrice Jacquelin, Gaël Petitjean, Désirée Kunkel, Anne-Sophie Liovat, Simon P Jochems, Kenneth A Rogers, Mickaël J Ploquin, Yoann Madec, Françoise Barré-Sinoussi, Nathalie Dereuddre-Bosquet, Pierre Lebon, Roger Le Grand, François Villinger, Michaela Müller-Trutwin
Published 2014-07-01

Extremely low viral reservoir in treated chronically HIV-1-infected individuals

by Cristina Gálvez, Victor Urrea, Judith Dalmau, Montse Jimenez, Bonaventura Clotet, Valérie Monceaux, Nicolas Huot, Lorna Leal, Victoria González-Soler, Maria González-Cao, Michaela Müller-Trutwin, Asier Sáez-Cirión, Felipe García, Julià Blanco, Javier Martinez-Picado, Maria Salgado
Published 2020-07-01

IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques

by Justin Harper, Nicolas Huot, Luca Micci, Gregory Tharp, Colin King, Philippe Rascle, Neeta Shenvi, Hong Wang, Cristin Galardi, Amit A. Upadhyay, Francois Villinger, Jeffrey Lifson, Guido Silvestri, Kirk Easley, Beatrice Jacquelin, Steven Bosinger, Michaela Müller-Trutwin, Mirko Paiardini
Published 2021-05-01

Second European Round Table on the Future Management of HIV

by Casper Rokx, Douglas D. Richman, Michaela Müller-Trutwin, Guido Silvestri, Jan Lunzen, van, Saye Khoo, Mathias Lichterfeld, Marcus Altfeld, Carlo Federico Perno, Peter W. Hunt, Paddy Mallon, Jürgen K. Rockstroh, Anton L. Pozniak, Bonaventura Clotet, Charles A.B. Boucher
Published 2015-07-01

CD32+CD4+ T Cells Sharing B Cell Properties Increase With Simian Immunodeficiency Virus Replication in Lymphoid Tissues

by Nicolas Huot, Philippe Rascle, Philippe Rascle, Cyril Planchais, Vanessa Contreras, Caroline Passaes, Roger Le Grand, Anne-Sophie Beignon, Etienne Kornobis, Etienne Kornobis, Rachel Legendre, Rachel Legendre, Hugo Varet, Hugo Varet, Asier Saez-Cirion, Hugo Mouquet, Beatrice Jacquelin, Michaela Müller-Trutwin
Published 2021-06-01

Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles.

by Chiraz Hamimi, Annie David, Pierre Versmisse, Laurence Weiss, Timothée Bruel, David Zucman, Victor Appay, Arnaud Moris, Marie-Noëlle Ungeheuer, Caroline Lascoux-Combe, Françoise Barré-Sinoussi, Michaela Muller-Trutwin, Faroudy Boufassa, Olivier Lambotte, Gianfranco Pancino, Asier Sáez-Cirión, ANRS CO21 CODEX cohort
Published 2016-01-01

SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity

by Nicolas Huot, Philippe Rascle, Caroline Petitdemange, Vanessa Contreras, Christina M. Stürzel, Eduard Baquero, Justin L. Harper, Caroline Passaes, Rachel Legendre, Hugo Varet, Yoann Madec, Ulrike Sauermann, Christiane Stahl-Hennig, Jacob Nattermann, Asier Saez-Cirion, Roger Le Grand, R. Keith Reeves, Mirko Paiardini, Frank Kirchhoff, Beatrice Jacquelin, Michaela Müller-Trutwin
Published 2021-02-01

Optimal Maturation of the SIV-Specific CD8+ T Cell Response after Primary Infection Is Associated with Natural Control of SIV: ANRS SIC Study

by Caroline Passaes, Antoine Millet, Vincent Madelain, Valérie Monceaux, Annie David, Pierre Versmisse, Naya Sylla, Emma Gostick, Sian Llewellyn-Lacey, David A. Price, Antoine Blancher, Nathalie Dereuddre-Bosquet, Delphine Desjardins, Gianfranco Pancino, Roger Le Grand, Olivier Lambotte, Michaela Müller-Trutwin, Christine Rouzioux, Jérémie Guedj, Véronique Avettand-Fenoel, Bruno Vaslin, Asier Sáez-Cirión
Published 2020-09-01

Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection.

by Abderaouf Damouche, Thierry Lazure, Véronique Avettand-Fènoël, Nicolas Huot, Nathalie Dejucq-Rainsford, Anne-Pascale Satie, Adeline Mélard, Ludivine David, Céline Gommet, Jade Ghosn, Nicolas Noel, Guillaume Pourcher, Valérie Martinez, Stéphane Benoist, Véronique Béréziat, Antonio Cosma, Benoit Favier, Bruno Vaslin, Christine Rouzioux, Jacqueline Capeau, Michaela Müller-Trutwin, Nathalie Dereuddre-Bosquet, Roger Le Grand, Olivier Lambotte, Christine Bourgeois
Published 2015-09-01

Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity

by Simone Joas, Erica H. Parrish, Clement W. Gnanadurai, Edina Lump, Christina M. Stürzel, Nicholas F. Parrish, Gerald H. Learn, Ulrike Sauermann, Berit Neumann, Kerstin Mätz Rensing, Dietmar Fuchs, James M. Billingsley, Steven E. Bosinger, Guido Silvestri, Cristian Apetrei, Nicolas Huot, Thalia Garcia-Tellez, Michaela Müller-Trutwin, Dominik Hotter, Daniel Sauter, Christiane Stahl-Hennig, Beatrice H. Hahn, Frank Kirchhoff
Published 2018-04-01

Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation

by Ang Lin, Sven Brandau, Stephan Lang, Luca Cassetta, Kirsten Bruderek, Joanna Skrzeczynska-Moncznik, Oktawia Osiecka, Xiaoying Hu, Ida Marie Rundgren, Kim Santegoets, Utku Horzum, Ana Godinho-Santos, Gennadiy Zelinskyy, Thalia Garcia-Tellez, Sunčica Bjelica, Bartłomiej Taciak, Astrid Olsnes Kittang, Benedikt Höing, Michael Dixon, Verena Müller, Jochen Sven Utikal, Derya Karakoç, Kerim Bora Yilmaz, Emilia Górka, Olympia Evdoxia Anastasiou, Christine Bourgeois, Robert Badura, Monika Kapinska-Mrowiecka, Mirjana Gotic, Mark ter Laan, Esther Kers-Rebel, Magdalena Król, Juan Francisco Santibañez, Michaela Müller-Trutwin, Ulf Dittmer, Ana Espada de Sousa, Güneş Esendağlı, Gosse Adema, Karin Loré, Elisabeth Ersvær, Viktor Umansky, Jeffrey W Pollard, Joanna Cichy
Published 2020-07-01