Genetic and epigenetic studies of adiposity and cardiometabolic disease

by Michael V. Holmes, Sara L. Pulit, Cecilia M. Lindgren
Published 2017-09-01

Fatal Lactic Acidosis in a Kidney Transplant Recipient on Combination Antiretroviral Therapy after Initiation of Tacrolimus Therapy

by Michael V. Holmes, Ranjababu Kulasegaram, Sebastian B. Lucas, Terry Wong, Rachel Hilton
Published 2011-01-01

CYP2D6 genotype and tamoxifen response for breast cancer: a systematic review and meta-analysis.

by Danny W K Lum, Pablo Perel, Aroon D Hingorani, Michael V Holmes
Published 2013-01-01

Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to severe SARS-CoV-2

by Tom G. Richardson, Si Fang, Ruth E. Mitchell, Michael V. Holmes, George Davey Smith
Published 2021-02-01

Genomic Research to Identify Novel Pathways in the Development of Abdominal Aortic Aneurysm

by Seamus C. Harrison, Anastasia Z. Kalea, Michael V. Holmes, Obi Agu, Steve E. Humphries
Published 2012-01-01

Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.

by Michael V Holmes, Tina Shah, Christine Vickery, Liam Smeeth, Aroon D Hingorani, Juan P Casas
Published 2009-12-01

GWAS identifies 14 loci for device-measured physical activity and sleep duration

by Aiden Doherty, Karl Smith-Byrne, Teresa Ferreira, Michael V. Holmes, Chris Holmes, Sara L. Pulit, Cecilia M. Lindgren
Published 2018-12-01

Paradoxical association of C-reactive protein with endothelial function in rheumatoid arthritis.

by Michael V Holmes, Benyu Jiang, Karen McNeill, Melinda Wong, Stephen P Oakley, Bruce Kirkham, Phil J Chowienczyk
Published 2010-04-01

Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.

by Tom G Richardson, Eleanor Sanderson, Tom M Palmer, Mika Ala-Korpela, Brian A Ference, George Davey Smith, Michael V Holmes
Published 2020-03-01

NMR Metabolite Profiles in Male Meat-Eaters, Fish-Eaters, Vegetarians and Vegans, and Comparison with MS Metabolite Profiles

by Julie A. Schmidt, Georgina K. Fensom, Sabina Rinaldi, Augustin Scalbert, Marc J. Gunter, Michael V. Holmes, Timothy J. Key, Ruth C. Travis
Published 2021-02-01

A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome

by Akira Wiberg, Michael Ng, Annina B. Schmid, Robert W. Smillie, Georgios Baskozos, Michael V. Holmes, K. Künnapuu, R. Mägi, David L. Bennett, Dominic Furniss
Published 2019-03-01

Causal relationships between obesity and the leading causes of death in women and men.

by Jenny C Censin, Sanne A E Peters, Jonas Bovijn, Teresa Ferreira, Sara L Pulit, Reedik Mägi, Anubha Mahajan, Michael V Holmes, Cecilia M Lindgren
Published 2019-10-01

Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study.

by Joshua A Bell, David Carslake, Kaitlin H Wade, Rebecca C Richmond, Ryan J Langdon, Emma E Vincent, Michael V Holmes, Nicholas J Timpson, George Davey Smith
Published 2018-08-01

Guidelines for performing Mendelian randomization investigations [version 2; peer review: 2 approved]

by Stephen Burgess, George Davey Smith, Neil M. Davies, Frank Dudbridge, Dipender Gill, M. Maria Glymour, Fernando P. Hartwig, Michael V. Holmes, Cosetta Minelli, Caroline L. Relton, Evropi Theodoratou
Published 2020-04-01

Bone mineral density and risk of type 2 diabetes and coronary heart disease: A Mendelian randomization study [version 1; referees: 2 approved, 1 approved with reservations]

by Wei Gan, Robert J. Clarke, Anubha Mahajan, Benard Kulohoma, Hidetoshi Kitajima, Neil R. Robertson, N. William Rayner, Robin G. Walters, Michael V. Holmes, Zhengming Chen, Mark I. McCarthy
Published 2017-08-01

Metabolic and lifestyle risk factors for acute pancreatitis in Chinese adults: A prospective cohort study of 0.5 million people.

by Yuanjie Pang, Christiana Kartsonaki, Iain Turnbull, Yu Guo, Ling Yang, Zheng Bian, Yiping Chen, Iona Y Millwood, Fiona Bragg, Weiwei Gong, Qinai Xu, Quan Kang, Junshi Chen, Liming Li, Michael V Holmes, Zhengming Chen
Published 2018-08-01

Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.

by Ling Lu, Derrick A Bennett, Iona Y Millwood, Sarah Parish, Mark I McCarthy, Anubha Mahajan, Xu Lin, Fiona Bragg, Yu Guo, Michael V Holmes, Shoaib Afzal, Børge G Nordestgaard, Zheng Bian, Michael Hill, Robin G Walters, Liming Li, Zhengming Chen, Robert Clarke
Published 2018-05-01

Mendelian randomization for studying the effects of perturbing drug targets [version 2; peer review: 2 approved, 1 approved with reservations]

by Dipender Gill, Marios K. Georgakis, Venexia M. Walker, A. Floriaan Schmidt, Apostolos Gkatzionis, Daniel F. Freitag, Chris Finan, Aroon D. Hingorani, Joanna M.M. Howson, Stephen Burgess, Daniel I. Swerdlow, George Davey Smith, Michael V. Holmes, Martin Dichgans, Robert A Scott, Jie Zheng, Bruce M. Psaty, Neil M. Davies
Published 2021-02-01

Effects of apolipoprotein B on lifespan and risks of major diseases including type 2 diabetes: a mendelian randomisation analysis using outcomes in first-degree relatives

by Tom G Richardson, PhD, Qin Wang, PhD, Eleanor Sanderson, PhD, Anubha Mahajan, PhD, Mark I McCarthy, ProfMD, Timothy M Frayling, ProfPhD, Mika Ala-Korpela, ProfPhD, Allan Sniderman, ProfMD, George Davey Smith, ProfFRS, Michael V Holmes, MD
Published 2021-06-01

Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition.

by Johannes Kettunen, Michael V Holmes, Elias Allara, Olga Anufrieva, Pauli Ohukainen, Clare Oliver-Williams, Qin Wang, Therese Tillin, Alun D Hughes, Mika Kähönen, Terho Lehtimäki, Jorma Viikari, Olli T Raitakari, Veikko Salomaa, Marjo-Riitta Järvelin, Markus Perola, George Davey Smith, Nish Chaturvedi, John Danesh, Emanuele Di Angelantonio, Adam S Butterworth, Mika Ala-Korpela
Published 2019-12-01