PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.

by Gema Medina-Gomez, Sarah L Gray, Laxman Yetukuri, Kenju Shimomura, Sam Virtue, Mark Campbell, R Keira Curtis, Mercedes Jimenez-Linan, Margaret Blount, Giles S H Yeo, Miguel Lopez, Tuulikki Seppänen-Laakso, Frances M Ashcroft, Matej Oresic, Antonio Vidal-Puig
Published 2007-04-01

Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective...

by Christine A Parkinson, Davina Gale, Anna M Piskorz, Heather Biggs, Charlotte Hodgkin, Helen Addley, Sue Freeman, Penelope Moyle, Evis Sala, Karen Sayal, Karen Hosking, Ioannis Gounaris, Mercedes Jimenez-Linan, Helena M Earl, Wendi Qian, Nitzan Rosenfeld, James D Brenton
Published 2016-12-01

Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.

by Roland F Schwarz, Charlotte K Y Ng, Susanna L Cooke, Scott Newman, Jillian Temple, Anna M Piskorz, Davina Gale, Karen Sayal, Muhammed Murtaza, Peter J Baldwin, Nitzan Rosenfeld, Helena M Earl, Evis Sala, Mercedes Jimenez-Linan, Christine A Parkinson, Florian Markowetz, James D Brenton
Published 2015-02-01

Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene.

by Lorenza Mittempergher, Anna M Piskorz, Astrid J Bosma, Magali Michaut, G Bea A Wisman, Roelof J C Kluin, Marja Nieuwland, Wim Brugman, Kevin J W van der Ven, Francesco Marass, James Morris, Nitzan Rosenfeld, Mercedes Jimenez-Linan, Steven de Jong, Ate G J van der Zee, James D Brenton, René Bernards
Published 2020-01-01

<i>PIK3R1</i>^W624R Is an Actionable Mutation in High Grade Serous Ovarian Carcinoma

by Concetta D’Ambrosio, Jessica Erriquez, Maddalena Arigoni, Sonia Capellero, Gloria Mittica, Eleonora Ghisoni, Fulvio Borella, Dionyssios Katsaros, Silvana Privitera, Marisa Ribotta, Elena Maldi, Giovanna Di Nardo, Enrico Berrino, Tiziana Venesio, Riccardo Ponzone, Marco Vaira, Douglas Hall, Mercedes Jimenez-Linan, Anna L. Paterson, Raffaele A. Calogero, James D. Brenton, Giorgio Valabrega, Maria Flavia Di Renzo, Martina Olivero
Published 2020-02-01

Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance.

by Christopher J Lelliott, Gema Medina-Gomez, Natasa Petrovic, Adrienn Kis, Helena M Feldmann, Mikael Bjursell, Nadeene Parker, Keira Curtis, Mark Campbell, Ping Hu, Dongfang Zhang, Sheldon E Litwin, Vlad G Zaha, Kimberly T Fountain, Sihem Boudina, Mercedes Jimenez-Linan, Margaret Blount, Miguel Lopez, Aline Meirhaeghe, Mohammad Bohlooly-Y, Leonard Storlien, Maria Strömstedt, Michael Snaith, Matej Oresic, E Dale Abel, Barbara Cannon, Antonio Vidal-Puig
Published 2006-11-01

Sodium MRI with 3D-cones as a measure of tumour cellularity in high grade serous ovarian cancer

by Surrin S. Deen, Frank Riemer, Mary A. McLean, Andrew B. Gill, Joshua D. Kaggie, James T. Grist, Robin Crawford, John Latimer, Peter Baldwin, Helena M. Earl, Christine A. Parkinson, Sarah A. Smith, Charlotte Hodgkin, Elizabeth Moore, Mercedes Jimenez-Linan, Cara R. Brodie, Helen C. Addley, Susan J. Freeman, Penelope L. Moyle, Evis Sala, Martin J. Graves, James D. Brenton, Ferdia A. Gallagher
Published 2019-01-01