Screening compounds with a novel high-throughput ABCB1-mediated efflux assay identifies drugs with known therapeutic targets at risk for multidrug resistance interference.

by Megan R Ansbro, Suneet Shukla, Suresh V Ambudkar, Stuart H Yuspa, Luowei Li
Published 2013-01-01

Development of copy number assays for detection and surveillance of piperaquine resistance associated plasmepsin 2/3 copy number variation in Plasmodium falciparum

by Megan R. Ansbro, Christopher G. Jacob, Roberto Amato, Mihir Kekre, Chanaki Amaratunga, Sokunthea Sreng, Seila Suon, Olivo Miotto, Rick M. Fairhurst, Thomas E. Wellems, Dominic P. Kwiatkowski
Published 2020-05-01

Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine

by Duangkamon Loesbanluechai, Namfon Kotanan, Cristina de Cozar, Theerarat Kochakarn, Megan R. Ansbro, Kesinee Chotivanich, Nicholas J. White, Prapon Wilairat, Marcus C.S. Lee, Francisco Javier Gamo, Laura Maria Sanz, Thanat Chookajorn, Krittikorn Kümpornsin
Published 2019-04-01