Computational Docking of Antibody-Antigen Complexes, Opportunities and Pitfalls Illustrated by Influenza Hemagglutinin

by Mattia Pedotti, Luca Simonelli, Elsa Livoti, Luca Varani
Published 2011-01-01

Rational engineering of the lccβ T. versicolor laccase for the mediator-less oxidation of large polycyclic aromatic hydrocarbons

by Alessandro Chiadò, Francesca Bosco, Marco Bardelli, Luca Simonelli, Mattia Pedotti, Luca Marmo, Luca Varani
Published 2021-01-01

Rational modification of estrogen receptor by combination of computational and experimental analysis.

by Valentina Elisabetta Viviana Ferrero, Mattia Pedotti, Alessandro Chiadò, Luca Simonelli, Luigi Calzolai, Luca Varani, Teresa Lettieri
Published 2014-01-01

Rationally Modified Estrogen Receptor Protein as a Bio-Recognition Element for the Detection of EDC Pollutants: Strategies and Opportunities

by Mattia Pedotti, Valentina Elisabetta Viviana Ferrero, Teresa Lettieri, Pascal Colpo, Stephane Follonier, Luigi Calzolai, Luca Varani
Published 2015-02-01

Rational engineering of a human anti-dengue antibody through experimentally validated computational docking.

by Luca Simonelli, Mattia Pedotti, Martina Beltramello, Elsa Livoti, Luigi Calzolai, Federica Sallusto, Antonio Lanzavecchia, Luca Varani
Published 2013-01-01

Label-Free Biosensor Detection of Endocrine Disrupting Compounds Using Engineered Estrogen Receptors

by Rita La Spina, Valentina E. V. Ferrero, Venera Aiello, Mattia Pedotti, Luca Varani, Teresa Lettieri, Luigi Calzolai, Willem Haasnoot, Pascal Colpo
Published 2017-12-01

A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity.

by Marco Bardelli, Karl Frontzek, Luca Simonelli, Simone Hornemann, Mattia Pedotti, Federica Mazzola, Manfredi Carta, Valeria Eckhardt, Rocco D'Antuono, Tommaso Virgilio, Santiago F González, Adriano Aguzzi, Luca Varani
Published 2018-10-01

SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface

by Federico Bertoglio, Doris Meier, Nora Langreder, Stephan Steinke, Ulfert Rand, Luca Simonelli, Philip Alexander Heine, Rico Ballmann, Kai-Thomas Schneider, Kristian Daniel Ralph Roth, Maximilian Ruschig, Peggy Riese, Kathrin Eschke, Yeonsu Kim, Dorina Schäckermann, Mattia Pedotti, Philipp Kuhn, Susanne Zock-Emmenthal, Johannes Wöhrle, Normann Kilb, Tobias Herz, Marlies Becker, Martina Grasshoff, Esther Veronika Wenzel, Giulio Russo, Andrea Kröger, Linda Brunotte, Stephan Ludwig, Viola Fühner, Stefan Daniel Krämer, Stefan Dübel, Luca Varani, Günter Roth, Luka Čičin-Šain, Maren Schubert, Michael Hust
Published 2021-03-01