Structural basis for germline antibody recognition of HIV-1 immunogens

by Louise Scharf, Anthony P West Jr, Stuart A Sievers, Courtney Chen, Siduo Jiang, Han Gao, Matthew D Gray, Andrew T McGuire, Johannes F Scheid, Michel C Nussenzweig, Leonidas Stamatatos, Pamela J Bjorkman
Published 2016-03-01

Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies

by Emilie Seydoux, Yu-Hsin Wan, Junli Feng, Abigail Wall, Safia Aljedani, Leah J. Homad, Anna J. MacCamy, Connor Weidle, Matthew D. Gray, Lauren Brumage, Justin J. Taylor, Marie Pancera, Leonidas Stamatatos, Andrew T. McGuire
Published 2021-05-01

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

by Andrew J Borst, Connor E Weidle, Matthew D Gray, Brandon Frenz, Joost Snijder, M Gordon Joyce, Ivelin S Georgiev, Guillaume BE Stewart-Jones, Peter D Kwong, Andrew T McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler
Published 2018-11-01

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice

by Andrew T. McGuire, Matthew D. Gray, Pia Dosenovic, Alexander D. Gitlin, Natalia T. Freund, John Petersen, Colin Correnti, William Johnsen, Robert Kegel, Andrew B. Stuart, Jolene Glenn, Michael S. Seaman, William R. Schief, Roland K. Strong, Michel C. Nussenzweig, Leonidas Stamatatos
Published 2016-02-01

Correction: HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.

by Celia C LaBranche, Andrew T McGuire, Matthew D Gray, Shay Behrens, Xuejun Chen, Tongqing Zhou, Quentin J Sattentau, James Peacock, Amanda Eaton, Kelli Greene, Hongmei Gao, Haili Tang, Lautaro G Perez, Kevin O Saunders, Peter D Kwong, John R Mascola, Barton F Haynes, Leonidas Stamatatos, David C Montefiori
Published 2019-03-01

HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.

by Celia C LaBranche, Andrew T McGuire, Matthew D Gray, Shay Behrens, Peter D Kwong, Xuejun Chen, Tongqing Zhou, Quentin J Sattentau, James Peacock, Amanda Eaton, Kelli Greene, Hongmei Gao, Haili Tang, Lautaro G Perez, Xuejun Chen, Kevin O Saunders, Peter D Kwong, John R Mascola, Barton F Haynes, Leonidas Stamatatos, David C Montefiori
Published 2018-11-01