Emerging Role of PYHIN Proteins as Antiviral Restriction Factors

by Matteo Bosso, Frank Kirchhoff
Published 2020-12-01

Cellular Factors Targeting HIV-1 Transcriptionand Viral RNA Transcripts

by Rayhane Nchioua, Matteo Bosso, Dorota Kmiec, Frank Kirchhoff
Published 2020-04-01

IFI16 knockdown in primary HIV-1 target cells

by Matteo Bosso, Caterina Prelli Bozzo, Meta Volcic, Frank Kirchhoff
Published 2021-03-01

An additional NF-κB site allows HIV-1 subtype C to evade restriction by nuclear PYHIN proteins

by Matteo Bosso, Christina M. Stürzel, Dorota Kmiec, Smitha Srinivasachar Badarinarayan, Elisabeth Braun, Jumpei Ito, Kei Sato, Beatrice H. Hahn, Konstantin M.J. Sparrer, Daniel Sauter, Frank Kirchhoff
Published 2021-09-01

Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.

by Matteo Bosso, Caterina Prelli Bozzo, Dominik Hotter, Meta Volcic, Christina M Stürzel, Annika Rammelt, Yi Ni, Stephan Urban, Miriam Becker, Mario Schelhaas, Sabine Wittmann, Maria H Christensen, Florian I Schmidt, Thomas Gramberg, Konstantin M J Sparrer, Daniel Sauter, Frank Kirchhoff
Published 2020-08-01