Systematic screening of 96 Schistosoma mansoni cell-surface and secreted antigens does not identify any strongly protective vaccine candidates in a mouse model of infection [versio...

by Cecile Crosnier, Cordelia Brandt, Gabriel Rinaldi, Catherine McCarthy, Colin Barker, Simon Clare, Matthew Berriman, Gavin J. Wright
Published 2019-10-01

Interferon lambda is required for interferon gamma-expressing NK cell responses but does not afford antiviral protection during acute and persistent murine cytomegalovirus infectio...

by Silvia Gimeno Brias, Morgan Marsden, Jessica Forbester, Mathew Clement, Cordelia Brandt, Katherine Harcourt, Leanne Kane, Lucy Chapman, Simon Clare, Ian R Humphreys
Published 2018-01-01

Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo.

by Georgina Awuah-Mensah, Jennifer McDonald, Pieter C Steketee, Delphine Autheman, Sarah Whipple, Simon D'Archivio, Cordelia Brandt, Simon Clare, Katherine Harcourt, Gavin J Wright, Liam J Morrison, Catarina Gadelha, Bill Wickstead
Published 2021-01-01

Baseline Gut Microbiota Composition Is Associated With Schistosoma mansoni Infection Burden in Rodent Models

by Alba Cortés, Alba Cortés, Simon Clare, Alice Costain, Alexandre Almeida, Alexandre Almeida, Catherine McCarthy, Katherine Harcourt, Cordelia Brandt, Charlotte Tolley, James Rooney, Matthew Berriman, Trevor Lawley, Andrew S. MacDonald, Gabriel Rinaldi, Cinzia Cantacessi
Published 2020-11-01

Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice.

by Trevor D Lawley, Simon Clare, Alan W Walker, Mark D Stares, Thomas R Connor, Claire Raisen, David Goulding, Roland Rad, Fernanda Schreiber, Cordelia Brandt, Laura J Deakin, Derek J Pickard, Sylvia H Duncan, Harry J Flint, Taane G Clark, Julian Parkhill, Gordon Dougan
Published 2012-01-01

Infection Susceptibility in Gastric Intrinsic Factor (Vitamin B12)-Defective Mice Is Subject to Maternal Influences

by Lynda Mottram, Anneliese O. Speak, Reza M. Selek, Emma L. Cambridge, Zoe McIntyre, Leanne Kane, Subhankar Mukhopadhyay, Carolyn Grove, Amy Colin, Cordelia Brandt, Maria A. Duque-Correa, Jessica Forbester, Tu Anh Pham Nguyen, Christine Hale, George S. Vasilliou, Mark J. Arends, Brendan W. Wren, Gordon Dougan, Simon Clare
Published 2016-06-01