Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice

by Tulasi Yadati, Tom Houben, Albert Bitorina, Yvonne Oligschlaeger, Marion J. Gijbels, Marion J. Gijbels, Ronny Mohren, Dieter Lütjohann, Princy Khurana, Sandeep Goyal, Aditya Kulkarni, Jan Theys, Berta Cillero-Pastor, Ronit Shiri-Sverdlov
Published 2021-07-01

Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis

by Renée J. H. A. Tillie, Jenny De Bruijn, Javier Perales-Patón, Javier Perales-Patón, Lieve Temmerman, Yanal Ghosheh, Kim Van Kuijk, Marion J. Gijbels, Marion J. Gijbels, Marion J. Gijbels, Peter Carmeliet, Peter Carmeliet, Peter Carmeliet, Klaus Ley, Klaus Ley, Julio Saez-Rodriguez, Julio Saez-Rodriguez, Judith C. Sluimer, Judith C. Sluimer
Published 2021-08-01

Examination of lipid profiles in abdominal fascial healing using MALDI-TOF to identify potential therapeutic targets

by Hong Liu, Jianhua Cao, Benjamin Balluff, Audrey C.H.M. Jongen, Marion J. Gijbels, Jarno Melenhorst, Ron M.A. Heeren, Nicole D. Bouvy
Published 2021-04-01

Wound administration of M2-polarized macrophages does not improve murine cutaneous healing responses.

by Nadine Jetten, Nadia Roumans, Marion J Gijbels, Andrea Romano, Mark J Post, Menno P J de Winther, Rene R W J van der Hulst, Sofia Xanthoulea
Published 2014-01-01

LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease.

by Veerle Bieghs, Patrick J Van Gorp, Kristiaan Wouters, Tim Hendrikx, Marion J Gijbels, Marc van Bilsen, Jaap Bakker, Christoph J Binder, Dieter Lütjohann, Bart Staels, Marten H Hofker, Ronit Shiri-Sverdlov
Published 2012-01-01

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice.

by Pathricia V Tilstam, Marion J Gijbels, Mohamed Habbeddine, Céline Cudejko, Yaw Asare, Wendy Theelen, Baixue Zhou, Yvonne Döring, Maik Drechsler, Lukas Pawig, Sakine Simsekyilmaz, Rory R Koenen, Menno P J de Winther, Toby Lawrence, Jürgen Bernhagen, Alma Zernecke, Christian Weber, Heidi Noels
Published 2014-01-01

Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice.

by Martine Bot, Paul P Van Veldhoven, Saskia C A de Jager, Jason Johnson, Niels Nijstad, Peter J Van Santbrink, Marijke M Westra, Gerd Van Der Hoeven, Marion J Gijbels, Carsten Müller-Tidow, Georg Varga, Uwe J F Tietge, Johan Kuiper, Theo J C Van Berkel, Jerzy-Roch Nofer, Ilze Bot, Erik A L Biessen
Published 2013-01-01