Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?

by Venus Sosa Iglesias, Lorena Giuranno, Ludwig J. Dubois, Jan Theys, Marc Vooijs
Published 2018-07-01

Efficient Secretion of Murine IL-2 From an Attenuated Strain of Clostridium sporogenes, a Novel Delivery Vehicle for Cancer Immunotherapy

by Aleksandra M. Kubiak, Aleksandra M. Kubiak, Tom S. Bailey, Ludwig J. Dubois, Jan Theys, Philippe Lambin
Published 2021-06-01

Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations.

by Roland K Chiu, Jan Brun, Chantal Ramaekers, Jan Theys, Lin Weng, Philippe Lambin, Douglas A Gray, Bradly G Wouters
Published 2006-07-01

Use of a Luciferase-Expressing Orthotopic Rat Brain Tumor Model to Optimize a Targeted Irradiation Strategy for Efficacy Testing with Temozolomide

by Alexandra M. Mowday, Natasja G. Lieuwes, Rianne Biemans, Damiënne Marcus, Behzad Rezaeifar, Brigitte Reniers, Frank Verhaegen, Jan Theys, Ludwig J. Dubois
Published 2020-06-01

Complementary Use of Bioluminescence Imaging and Contrast-Enhanced Micro—Computed Tomography in an Orthotopic Brain Tumor Model

by Sanaz Yahyanejad, Patrick V. Granton, Natasja G. Lieuwes, Lesley Gilmour, Ludwig Dubois, Jan Theys, Anthony J. Chalmers, Frank Verhaegen, Marc Vooijs
Published 2014-01-01

Nutritional Interventions in Cancer Cachexia: Evidence and Perspectives From Experimental Models

by Wouter R. P. H. van de Worp, Annemie M. W. J. Schols, Jan Theys, Ardy van Helvoort, Ardy van Helvoort, Ramon C. J. Langen
Published 2020-12-01

Human fibronectin extra domain B as a biomarker for targeted therapy in cancer

by Relinde I. Y. Lieverse, Damiënne Marcus, Alexander M. A. van derWiel, Evert J. Van Limbergen, Jan Theys, Ala Yaromina, Philippe Lambin, Ludwig J. Dubois
Published 2020-07-01

Advancing Clostridia to Clinical Trial: Past Lessons and Recent Progress

by Alexandra M. Mowday, Christopher P. Guise, David F. Ackerley, Nigel P. Minton, Philippe Lambin, Ludwig J. Dubois, Jan Theys, Jeff B. Smaill, Adam V. Patterson
Published 2016-06-01

Hypoxia-activated prodrugs and (lack of) clinical progress: The need for hypoxia-based biomarker patient selection in phase III clinical trials

by Linda Spiegelberg, Ruud Houben, Raymon Niemans, Dirk de Ruysscher, Ala Yaromina, Jan Theys, Christopher P. Guise, Jeffrey B. Smaill, Adam V. Patterson, Philippe Lambin, Ludwig J. Dubois
Published 2019-02-01

Synergistic Effects of NOTCH/γ-Secretase Inhibition and Standard of Care Treatment Modalities in Non-small Cell Lung Cancer Cells

by Venus Sosa Iglesias, Jan Theys, Arjan J. Groot, Lydie M. O. Barbeau, Alyssa Lemmens, Ala Yaromina, Mario Losen, Ruud Houben, Ruud Houben, Ludwig Dubois, Marc Vooijs, Marc Vooijs
Published 2018-11-01

Hypoxia PET Imaging with [18F]-HX4—A Promising Next-Generation Tracer

by Sebastian Sanduleanu, Alexander M.A. van der Wiel, Relinde I.Y. Lieverse, Damiënne Marcus, Abdalla Ibrahim, Sergey Primakov, Guangyao Wu, Jan Theys, Ala Yaromina, Ludwig J. Dubois, Philippe Lambin
Published 2020-05-01

Deep Learning Based Automated Orthotopic Lung Tumor Segmentation in Whole-Body Mouse CT-Scans

by Wouter R. P. H. van de Worp, Brent van der Heyden, Georgios Lappas, Ardy van Helvoort, Jan Theys, Annemie M. W. J. Schols, Frank Verhaegen, Ramon C. J. Langen
Published 2021-09-01

Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy

by Veronica Olivo Pimentel, Damiënne Marcus, Alexander MA van der Wiel, Natasja G Lieuwes, Rianne Biemans, Relinde IY Lieverse, Dario Neri, Jan Theys, Ala Yaromina, Ludwig J Dubois, Philippe Lambin
Published 2021-03-01

Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice

by Tulasi Yadati, Tom Houben, Albert Bitorina, Yvonne Oligschlaeger, Marion J. Gijbels, Marion J. Gijbels, Ronny Mohren, Dieter Lütjohann, Princy Khurana, Sandeep Goyal, Aditya Kulkarni, Jan Theys, Berta Cillero-Pastor, Ronit Shiri-Sverdlov
Published 2021-07-01

Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice.

by Mike L J Jeurissen, Sofie M A Walenbergh, Tom Houben, Tim Hendrikx, Jieyi Li, Yvonne Oligschlaeger, Patrick J van Gorp, Marion J J Gijbels, Albert Bitorina, Isabell Nessel, Freddy Radtke, Marc Vooijs, Jan Theys, Ronit Shiri-Sverdlov
Published 2016-01-01

Identification of microRNAs in skeletal muscle associated with lung cancer cachexia

by Wouter R.P.H. van deWorp, Annemie M.W.J. Schols, Anne‐Marie C. Dingemans, Céline M.H. Op den Kamp, Juliette H.R.J. Degens, Marco C.J.M. Kelders, Susan Coort, Henry C. Woodruff, Gueorqui Kratassiouk, Annick Harel‐Bellan, Jan Theys, Ardy vanHelvoort, Ramon C.J. Langen
Published 2020-04-01