Manufacturing of Human Extracellular Vesicle-Based Therapeutics for Clinical Use

by Mario Gimona, Karin Pachler, Sandra Laner-Plamberger, Katharina Schallmoser, Eva Rohde
Published 2017-06-01

Candida albicans AGE3, the ortholog of the S. cerevisiae ARF-GAP-encoding gene GCS1, is required for hyphal growth and drug resistance.

by Thomas Lettner, Ute Zeidler, Mario Gimona, Michael Hauser, Michael Breitenbach, Arnold Bito
Published 2010-01-01

Dystroglycan, Tks5 and Src mediated assembly of podosomes in myoblasts.

by Oliver Thompson, Iivari Kleino, Luca Crimaldi, Mario Gimona, Kalle Saksela, Steve J Winder
Published 2008-01-01

Mesenchymal Stromal Cell-Based Bone Regeneration Therapies: From Cell Transplantation and Tissue Engineering to Therapeutic Secretomes and Extracellular Vesicles

by Darja Marolt Presen, Darja Marolt Presen, Andreas Traweger, Andreas Traweger, Mario Gimona, Heinz Redl, Heinz Redl
Published 2019-11-01

An In Vitro Potency Assay for Monitoring the Immunomodulatory Potential of Stromal Cell-Derived Extracellular Vesicles

by Karin Pachler, Nina Ketterl, Alexandre Desgeorges, Zsuzsanna A. Dunai, Sandra Laner-Plamberger, Doris Streif, Dirk Strunk, Eva Rohde, Mario Gimona
Published 2017-07-01

First‐in‐human intracochlear application of human stromal cell‐derived extracellular vesicles

by Athanasia Warnecke, Nils Prenzler, Jennifer Harre, Ulrike Köhl, Lutz Gärtner, Thomas Lenarz, Sandra Laner‐Plamberger, Georg Wietzorrek, Hinrich Staecker, Teresa Lassacher, Julia Hollerweger, Mario Gimona, Eva Rohde
Published 2021-06-01

Extracellular Vesicles Can Deliver Anti-inflammatory and Anti-scarring Activities of Mesenchymal Stromal Cells After Spinal Cord Injury

by Pasquale Romanelli, Pasquale Romanelli, Lara Bieler, Lara Bieler, Cornelia Scharler, Cornelia Scharler, Karin Pachler, Karin Pachler, Christina Kreutzer, Christina Kreutzer, Pia Zaunmair, Pia Zaunmair, Dominika Jakubecova, Dominika Jakubecova, Heike Mrowetz, Heike Mrowetz, Bruno Benedetti, Bruno Benedetti, Francisco J. Rivera, Francisco J. Rivera, Francisco J. Rivera, Francisco J. Rivera, Ludwig Aigner, Ludwig Aigner, Ludwig Aigner, Eva Rohde, Eva Rohde, Eva Rohde, Mario Gimona, Mario Gimona, Dirk Strunk, Dirk Strunk, Sebastien Couillard-Despres, Sebastien Couillard-Despres, Sebastien Couillard-Despres
Published 2019-11-01

Extracellular vesicles from human multipotent stromal cells protect against hearing loss after noise trauma in vivo

by Athanasia Warnecke, Jennifer Harre, Hinrich Staecker, Nils Prenzler, Dirk Strunk, Sebastien Couillard‐Despres, Pasquale Romanelli, Julia Hollerweger, Teresa Lassacher, Daniela Auer, Karin Pachler, Georg Wietzorrek, Ulrike Köhl, Thomas Lenarz, Katharina Schallmoser, Sandra Laner‐Plamberger, Christine S. Falk, Eva Rohde, Mario Gimona
Published 2020-12-01

Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications

by Kenneth W. Witwer, Bas W.M. Van Balkom, Stefania Bruno, Andre Choo, Massimo Dominici, Mario Gimona, Andrew F. Hill, Dominique De Kleijn, Mickey Koh, Ruenn Chai Lai, S. Alex Mitsialis, Luis A. Ortiz, Eva Rohde, Takashi Asada, Wei Seong Toh, Daniel J. Weiss, Lei Zheng, Bernd Giebel, Sai Kiang Lim
Published 2019-12-01

Concise Review: Developing Best‐Practice Models for the Therapeutic Use of Extracellular Vesicles

by Agnes T. Reiner, Kenneth W. Witwer, Bas W.M. van Balkom, Joel de Beer, Chaya Brodie, Randolph L. Corteling, Susanne Gabrielsson, Mario Gimona, Ahmed G. Ibrahim, Dominique de Kleijn, Charles P. Lai, Jan Lötvall, Hernando A. del Portillo, Ilona G. Reischl, Milad Riazifar, Carlos Salomon, Hidetoshi Tahara, Wei Seong Toh, Marca H.M. Wauben, Vicky K. Yang, Yijun Yang, Ronne Wee Yeh Yeo, Hang Yin, Bernd Giebel, Eva Rohde, Sai Kiang Lim
Published 2017-08-01

Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper

by Thomas Lener, Mario Gimona, Ludwig Aigner, Verena Börger, Edit Buzas, Giovanni Camussi, Nathalie Chaput, Devasis Chatterjee, Felipe A. Court, Hernando A. del Portillo, Lorraine O'Driscoll, Stefano Fais, Juan M. Falcon-Perez, Ursula Felderhoff-Mueser, Lorenzo Fraile, Yong Song Gho, André Görgens, Ramesh C. Gupta, An Hendrix, Dirk M. Hermann, Andrew F. Hill, Fred Hochberg, Peter A. Horn, Dominique de Kleijn, Lambros Kordelas, Boris W. Kramer, Eva-Maria Krämer-Albers, Sandra Laner-Plamberger, Saara Laitinen, Tommaso Leonardi, Magdalena J. Lorenowicz, Sai Kiang Lim, Jan Lötvall, Casey A. Maguire, Antonio Marcilla, Irina Nazarenko, Takahiro Ochiya, Tushar Patel, Shona Pedersen, Gabriella Pocsfalvi, Stefano Pluchino, Peter Quesenberry, Ilona G. Reischl, Francisco J. Rivera, Ralf Sanzenbacher, Katharina Schallmoser, Ineke Slaper-Cortenbach, Dirk Strunk, Torsten Tonn, Pieter Vader, Bas W. M. van Balkom, Marca Wauben, Samir El Andaloussi, Clotilde Théry, Eva Rohde, Bernd Giebel
Published 2015-12-01

Biological properties of extracellular vesicles and their physiological functions

by María Yáñez-Mó, Pia R.-M. Siljander, Zoraida Andreu, Apolonija Bedina Zavec, Francesc E. Borràs, Edit I. Buzas, Krisztina Buzas, Enriqueta Casal, Francesco Cappello, Joana Carvalho, Eva Colás, Anabela Cordeiro-da Silva, Stefano Fais, Juan M. Falcon-Perez, Irene M. Ghobrial, Bernd Giebel, Mario Gimona, Michael Graner, Ihsan Gursel, Mayda Gursel, Niels H. H. Heegaard, An Hendrix, Peter Kierulf, Katsutoshi Kokubun, Maja Kosanovic, Veronika Kralj-Iglic, Eva-Maria Krämer-Albers, Saara Laitinen, Cecilia Lässer, Thomas Lener, Erzsébet Ligeti, Aija Linē, Georg Lipps, Alicia Llorente, Jan Lötvall, Mateja Manček-Keber, Antonio Marcilla, Maria Mittelbrunn, Irina Nazarenko, Esther N.M. Nolte-‘t Hoen, Tuula A. Nyman, Lorraine O'Driscoll, Mireia Olivan, Carla Oliveira, Éva Pállinger, Hernando A. del Portillo, Jaume Reventós, Marina Rigau, Eva Rohde, Marei Sammar, Francisco Sánchez-Madrid, N. Santarém, Katharina Schallmoser, Marie Stampe Ostenfeld, Willem Stoorvogel, Roman Stukelj, Susanne G. Van der Grein, M. Helena Vasconcelos, Marca H. M. Wauben, Olivier De Wever
Published 2015-05-01

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014...

by Clotilde Théry, Kenneth W Witwer, Elena Aikawa, Maria Jose Alcaraz, Johnathon D Anderson, Ramaroson Andriantsitohaina, Anna Antoniou, Tanina Arab, Fabienne Archer, Georgia K Atkin-Smith, D Craig Ayre, Jean-Marie Bach, Daniel Bachurski, Hossein Baharvand, Leonora Balaj, Shawn Baldacchino, Natalie N Bauer, Amy A Baxter, Mary Bebawy, Carla Beckham, Apolonija Bedina Zavec, Abderrahim Benmoussa, Anna C Berardi, Paolo Bergese, Ewa Bielska, Cherie Blenkiron, Sylwia Bobis-Wozowicz, Eric Boilard, Wilfrid Boireau, Antonella Bongiovanni, Francesc E Borràs, Steffi Bosch, Chantal M Boulanger, Xandra Breakefield, Andrew M Breglio, Meadhbh Á Brennan, David R Brigstock, Alain Brisson, Marike LD Broekman, Jacqueline F Bromberg, Paulina Bryl-Górecka, Shilpa Buch, Amy H Buck, Dylan Burger, Sara Busatto, Dominik Buschmann, Benedetta Bussolati, Edit I Buzás, James Bryan Byrd, Giovanni Camussi, David RF Carter, Sarah Caruso, Lawrence W Chamley, Yu-Ting Chang, Chihchen Chen, Shuai Chen, Lesley Cheng, Andrew R Chin, Aled Clayton, Stefano P Clerici, Alex Cocks, Emanuele Cocucci, Robert J Coffey, Anabela Cordeiro-da-Silva, Yvonne Couch, Frank AW Coumans, Beth Coyle, Rossella Crescitelli, Miria Ferreira Criado, Crislyn D’Souza-Schorey, Saumya Das, Amrita Datta Chaudhuri, Paola de Candia, Eliezer F De Santana, Olivier De Wever, Hernando A del Portillo, Tanguy Demaret, Sarah Deville, Andrew Devitt, Bert Dhondt, Dolores Di Vizio, Lothar C Dieterich, Vincenza Dolo, Ana Paula Dominguez Rubio, Massimo Dominici, Mauricio R Dourado, Tom AP Driedonks, Filipe V Duarte, Heather M Duncan, Ramon M Eichenberger, Karin Ekström, Samir EL Andaloussi, Celine Elie-Caille, Uta Erdbrügger, Juan M Falcón-Pérez, Farah Fatima, Jason E Fish, Miguel Flores-Bellver, András Försönits, Annie Frelet-Barrand, Fabia Fricke, Gregor Fuhrmann, Susanne Gabrielsson, Ana Gámez-Valero, Chris Gardiner, Kathrin Gärtner, Raphael Gaudin, Yong Song Gho, Bernd Giebel, Caroline Gilbert, Mario Gimona, Ilaria Giusti, Deborah CI Goberdhan, André Görgens, Sharon M Gorski, David W Greening, Julia Christina Gross, Alice Gualerzi, Gopal N Gupta, Dakota Gustafson, Aase Handberg, Reka A Haraszti, Paul Harrison, Hargita Hegyesi, An Hendrix, Andrew F Hill, Fred H Hochberg, Karl F Hoffmann, Beth Holder, Harry Holthofer, Baharak Hosseinkhani, Guoku Hu, Yiyao Huang, Veronica Huber, Stuart Hunt, Ahmed Gamal-Eldin Ibrahim, Tsuneya Ikezu, Jameel M Inal, Mustafa Isin, Alena Ivanova, Hannah K Jackson, Soren Jacobsen, Steven M Jay, Muthuvel Jayachandran, Guido Jenster, Lanzhou Jiang, Suzanne M Johnson, Jennifer C Jones, Ambrose Jong, Tijana Jovanovic-Talisman, Stephanie Jung, Raghu Kalluri, Shin-ichi Kano, Sukhbir Kaur, Yumi Kawamura, Evan T Keller, Delaram Khamari, Elena Khomyakova, Anastasia Khvorova, Peter Kierulf, Kwang Pyo Kim, Thomas Kislinger, Mikael Klingeborn, David J Klinke, Miroslaw Kornek, Maja M Kosanović, Árpád Ferenc Kovács, Eva-Maria Krämer-Albers, Susanne Krasemann, Mirja Krause, Igor V Kurochkin, Gina D Kusuma, Sören Kuypers, Saara Laitinen, Scott M Langevin, Lucia R Languino, Joanne Lannigan, Cecilia Lässer, Louise C Laurent, Gregory Lavieu, Elisa Lázaro-Ibáñez, Soazig Le Lay, Myung-Shin Lee, Yi Xin Fiona Lee, Debora S Lemos, Metka Lenassi, Aleksandra Leszczynska, Isaac TS Li, Ke Liao, Sten F Libregts, Erzsebet Ligeti, Rebecca Lim, Sai Kiang Lim, Aija Linē, Karen Linnemannstöns, Alicia Llorente, Catherine A Lombard, Magdalena J Lorenowicz, Ákos M Lörincz, Jan Lötvall, Jason Lovett, Michelle C Lowry, Xavier Loyer, Quan Lu, Barbara Lukomska, Taral R Lunavat, Sybren LN Maas, Harmeet Malhi, Antonio Marcilla, Jacopo Mariani, Javier Mariscal, Elena S Martens-Uzunova, Lorena Martin-Jaular, M Carmen Martinez, Vilma Regina Martins, Mathilde Mathieu, Suresh Mathivanan, Marco Maugeri, Lynda K McGinnis, Mark J McVey, David G Meckes, Katie L Meehan, Inge Mertens, Valentina R Minciacchi, Andreas Möller, Malene Møller Jørgensen, Aizea Morales-Kastresana, Jess Morhayim, François Mullier, Maurizio Muraca, Luca Musante, Veronika Mussack, Dillon C Muth, Kathryn H Myburgh, Tanbir Najrana, Muhammad Nawaz, Irina Nazarenko, Peter Nejsum, Christian Neri, Tommaso Neri, Rienk Nieuwland, Leonardo Nimrichter, John P Nolan, Esther NM Nolte-’t Hoen, Nicole Noren Hooten, Lorraine O’Driscoll, Tina O’Grady, Ana O’Loghlen, Takahiro Ochiya, Martin Olivier, Alberto Ortiz, Luis A Ortiz, Xabier Osteikoetxea, Ole Østergaard, Matias Ostrowski, Jaesung Park, D. Michiel Pegtel, Hector Peinado, Francesca Perut, Michael W Pfaffl, Donald G Phinney, Bartijn CH Pieters, Ryan C Pink, David S Pisetsky, Elke Pogge von Strandmann, Iva Polakovicova, Ivan KH Poon, Bonita H Powell, Ilaria Prada, Lynn Pulliam, Peter Quesenberry, Annalisa Radeghieri, Robert L Raffai, Stefania Raimondo, Janusz Rak, Marcel I Ramirez, Graça Raposo, Morsi S Rayyan, Neta Regev-Rudzki, Franz L Ricklefs, Paul D Robbins, David D Roberts, Silvia C Rodrigues, Eva Rohde, Sophie Rome, Kasper MA Rouschop, Aurelia Rughetti, Ashley E Russell, Paula Saá, Susmita Sahoo, Edison Salas-Huenuleo, Catherine Sánchez, Julie A Saugstad, Meike J Saul, Raymond M Schiffelers, Raphael Schneider, Tine Hiorth Schøyen, Aaron Scott, Eriomina Shahaj, Shivani Sharma, Olga Shatnyeva, Faezeh Shekari, Ganesh Vilas Shelke, Ashok K Shetty, Kiyotaka Shiba, Pia R-M Siljander, Andreia M Silva, Agata Skowronek, Orman L Snyder, Rodrigo Pedro Soares, Barbara W Sódar, Carolina Soekmadji, Javier Sotillo, Philip D Stahl, Willem Stoorvogel, Shannon L Stott, Erwin F Strasser, Simon Swift, Hidetoshi Tahara, Muneesh Tewari, Kate Timms, Swasti Tiwari, Rochelle Tixeira, Mercedes Tkach, Wei Seong Toh, Richard Tomasini, Ana Claudia Torrecilhas, Juan Pablo Tosar, Vasilis Toxavidis, Lorena Urbanelli, Pieter Vader, Bas WM van Balkom, Susanne G van der Grein, Jan Van Deun, Martijn JC van Herwijnen, Kendall Van Keuren-Jensen, Guillaume van Niel, Martin E van Royen, Andre J van Wijnen, M Helena Vasconcelos, Ivan J Vechetti, Tiago D Veit, Laura J Vella, Émilie Velot, Frederik J Verweij, Beate Vestad, Jose L Viñas, Tamás Visnovitz, Krisztina V Vukman, Jessica Wahlgren, Dionysios C Watson, Marca HM Wauben, Alissa Weaver, Jason P Webber, Viktoria Weber, Ann M Wehman, Daniel J Weiss, Joshua A Welsh, Sebastian Wendt, Asa M Wheelock, Zoltán Wiener, Leonie Witte, Joy Wolfram, Angeliki Xagorari, Patricia Xander, Jing Xu, Xiaomei Yan, María Yáñez-Mó, Hang Yin, Yuana Yuana, Valentina Zappulli, Jana Zarubova, Vytautas Žėkas, Jian-ye Zhang, Zezhou Zhao, Lei Zheng, Alexander R Zheutlin, Antje M Zickler, Pascale Zimmermann, Angela M Zivkovic, Davide Zocco, Ewa K Zuba-Surma
Published 2018-12-01